hydroxymethylbilane synthase [Salmonella enterica].

LOCUS       WP_000219148             318 aa            linear   BCT 01-JUL-2024
ACCESSION   WP_000219148
VERSION     WP_000219148.1
KEYWORDS    RefSeq.
SOURCE      Salmonella enterica
  ORGANISM  Salmonella enterica
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Salmonella.
REFERENCE   1  (residues 1 to 318)
  AUTHORS   Louie,G.V., Brownlie,P.D., Lambert,R., Cooper,J.B., Blundell,T.L.,
            Wood,S.P., Malashkevich,V.N., Hadener,A., Warren,M.J. and
            Shoolingin-Jordan,P.M.
  TITLE     The three-dimensional structure of Escherichia coli porphobilinogen
            deaminase at 1.76-A resolution
  JOURNAL   Proteins 25 (1), 48-78 (1996)
   PUBMED   8727319
REFERENCE   2  (residues 1 to 318)
  AUTHORS   Fujino,E., Fujino,T., Karita,S., Sakka,K. and Ohmiya,K.
  TITLE     Cloning and sequencing of some genes responsible for porphyrin
            biosynthesis from the anaerobic bacterium Clostridium josui
  JOURNAL   J Bacteriol 177 (17), 5169-5175 (1995)
   PUBMED   7665501
REFERENCE   3  (residues 1 to 318)
  AUTHORS   Hadener,A., Matzinger,P.K., Malashkevich,V.N., Louie,G.V.,
            Wood,S.P., Oliver,P., Alefounder,P.R., Pitt,A.R., Abell,C. and
            Battersby,A.R.
  TITLE     Purification, characterization, crystallisation and X-ray analysis
            of selenomethionine-labelled hydroxymethylbilane synthase from
            Escherichia coli
  JOURNAL   Eur J Biochem 211 (3), 615-624 (1993)
   PUBMED   8436121
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00212.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..318
                     /organism="Salmonella enterica"
                     /db_xref="taxon:28901"
     gene            1..318
                     /gene="hemC"
     Protein         1..318
                     /product="hydroxymethylbilane synthase"
                     /EC_number="2.5.1.61"
                     /GO_function="GO:0004418 - hydroxymethylbilane synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0033014 - tetrapyrrole biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=34102
     Region          9..312
                     /region_name="HemC"
                     /note="Porphobilinogen deaminase [Coenzyme transport and
                     metabolism]; COG0181"
                     /db_xref="CDD:439951"
ORIGIN      
        1 mtvtsmldnv lriatrqspl alwqahyvkd almathpglt velvpmvtrg dvildtplak
       61 vggkglfvke leiallekra diavhsmkdv pvafpdglgl vticeredpr dafvsnkyhs
      121 lddlpagsiv gtsslrrqcq laerrpdlii rslrgnvgtr lgkldngdyd aiilavaglk
      181 rlglesrirt alppdvslpa vgqgavgiec rlddartqal laplnhsqta lrvtaeramn
      241 trleggcqvp igsyaeiing eiwlralvga pdgsvmvrge rrgspeqaeq mgislaeell
      301 engarailte vyngetpa