MULTISPECIES: MFS transporter [Salmonella].

LOCUS       WP_000217433             403 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_000217433
VERSION     WP_000217433.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 403)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 403)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 403)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13024414
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     Protein         1..403
                     /product="MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=42053
     Region          15..379
                     /region_name="MFS_MosC_like"
                     /note="Membrane protein MosC and similar proteins of the
                     Major Facilitator Superfamily of transporters; cd17393"
                     /db_xref="CDD:340951"
     Site            order(24..25,28..29,32,64,117..118,120..122,125,144,
                     147..148,151,224,227..228,231..233,236,264,268,317..318,
                     322,326,341,344..345,348..349,352)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340951"
ORIGIN      
        1 mtvlssrnal krrtwalfmf fflpgllmas watrtpaird ilsvstaemg avlfglsigs
       61 msgilcsawl vkrfgtrkvi rttmtcavtg mvilsvalwc asplifalgl avfgasfgaa
      121 evainvegaa verelnktvl pmmhgfysfg tlagagvgma ltalsvpani hiilaaavai
      181 apifiairai pdgtgknase dshlqekglp fyrdiqllli gvvvlamafa egsandwlpl
      241 lmvdghgfsp tsgsliyagf tlgmtvgrft ggwfidrysr vtvvrasalm galgigliif
      301 vdsdwvagvs vilwglgasl gfpltisaas dtgpdaptrv svvattgyla flvgppllgy
      361 lgehyglrsa mmvvlalvil aalvakavak pvstpqpvme hna