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MULTISPECIES: UDP-2,3-diacylglucosamine diphosphatase [Salmonella].


LOCUS       WP_000212284             240 aa            linear   BCT 04-JUN-2024
ACCESSION   WP_000212284
VERSION     WP_000212284.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 240)
  AUTHORS   Babinski,K.J., Kanjilal,S.J. and Raetz,C.R.
  TITLE     Accumulation of the lipid A precursor UDP-2,3-diacylglucosamine in
            an Escherichia coli mutant lacking the lpxH gene
  JOURNAL   J Biol Chem 277 (29), 25947-25956 (2002)
   PUBMED   12000771
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01854.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..240
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..240
                     /gene="lpxH"
     Protein         1..240
                     /product="UDP-2,3-diacylglucosamine diphosphatase"
                     /EC_number="3.6.1.54"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008758 - UDP-2,3-diacylglucosamine
                     hydrolase activity [Evidence IEA]"
                     /GO_function="GO:0016462 - pyrophosphatase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009245 - lipid A biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=26847
     Region          1..240
                     /region_name="PRK05340"
                     /note="UDP-2,3-diacylglucosamine hydrolase; Provisional"
                     /db_xref="CDD:235420"
     Site            order(8,10,41,79..80,114,195,197)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:277343"
     Site            order(8,10,41,79,114,195,197)
                     /site_type="other"
                     /note="putative metal binding site [ion binding]"
                     /db_xref="CDD:277343"
ORIGIN      
        1 matlfiadlh lqteepaiva gflrflavea rqadalyilg dlfeawigdd dpnplhrema
       61 vaikslvdsg vpcffihgnr dfligkrfar esgmillpqe kvldlygrnv limhgdtlct
      121 ddagyqafra kvhnpwvqrl fltlplfirr riaarmrags kaanssksld imdvnaqtvv
      181 aemekhrvqw lihghthrpa vhelsandqp afrvvlgawh hegsmvkvtp dnveliafpl