MULTISPECIES: NADPH-dependent assimilatory sulfite reductase

LOCUS       WP_000211949             599 aa            linear   BCT 17-NOV-2023
            flavoprotein subunit [Shigella].
ACCESSION   WP_000211949
VERSION     WP_000211949.1
KEYWORDS    RefSeq.
SOURCE      Shigella
  ORGANISM  Shigella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008197.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10953
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..599
                     /organism="Shigella"
                     /db_xref="taxon:620"
     gene            1..599
                     /gene="cysJ"
     Protein         1..599
                     /product="NADPH-dependent assimilatory sulfite reductase
                     flavoprotein subunit"
                     /EC_number="1.8.1.2"
                     /GO_function="GO:0004783 - sulfite reductase (NADPH)
                     activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_process="GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /GO_process="GO:0019344 - cysteine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=66212
     Region          1..599
                     /region_name="cysJ"
                     /note="NADPH-dependent assimilatory sulfite reductase
                     flavoprotein subunit; PRK10953"
                     /db_xref="CDD:182862"
     Site            order(275,386..389,404,406,419..422)
                     /site_type="other"
                     /note="FAD binding pocket [chemical binding]"
                     /db_xref="CDD:99796"
     Site            order(386,388..389)
                     /site_type="other"
                     /note="FAD binding motif [chemical binding]"
                     /db_xref="CDD:99796"
     Site            order(389,552,597,599)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:99796"
     Site            order(406..409,460,462,489..490,519..520,527,529,558)
                     /site_type="other"
                     /note="NAD binding pocket [chemical binding]"
                     /db_xref="CDD:99796"
     Site            order(419,422,425)
                     /site_type="other"
                     /note="phosphate binding motif [ion binding]"
                     /db_xref="CDD:99796"
     Site            order(457,461..464,466)
                     /site_type="other"
                     /note="beta-alpha-beta structure motif"
                     /db_xref="CDD:99796"
ORIGIN      
        1 mttqvppsal lplnpeqlar lqaattdltp tqlawvsgyf wgvlnqqpva lavtpapaae
       61 mpgitiisas qtgnarrvae alrddllaak lnvklvnagd ykfkqiasek llivvtstqg
      121 egeppeeava lhkflfskka pklentafav fslgdssyef fcqsgkdfds klaelggerl
      181 ldrvdsdvey qaaasewrar vvdalksrap vaapsqsvat gavneihtsp yskdaplvas
      241 lsvnqkitgr nsekdvrhie idlgdsglry qpgdalgvwy qndpalvkel vellwltgde
      301 pvtvegktlp lnealqwhfe ltvntanive nyatltrset llplvgdkak lqhyaattli
      361 vdmvrfspaq ldaealinll rpltprlysi assqaevene vhvtvgvvry dvegraragg
      421 assfladrve eegevrvfie hndnfrlpan letpvimigp gtgiapfraf mqqraadeap
      481 gknwlffgnp hftedflyqv ewqryvkegv ltridlawsr dqkekvyvqd klreqgaelw
      541 rwindgahiy vcgdanrmak dveqallevi aefggmdtea adeflselrv erryqrdvy