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MULTISPECIES: argininosuccinate synthase [Enterobacteriaceae].


LOCUS       WP_000207680             447 aa            linear   BCT 16-DEC-2020
ACCESSION   WP_000207680
VERSION     WP_000207680.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 447)
  AUTHORS   Lemke,C.T. and Howell,P.L.
  TITLE     The 1.6 A crystal structure of E. coli argininosuccinate synthetase
            suggests a conformational change during catalysis
  JOURNAL   Structure 9 (12), 1153-1164 (2001)
   PUBMED   11738042
REFERENCE   2  (residues 1 to 447)
  AUTHORS   Lemke,C., Yeung,M. and Howell,P.L.
  TITLE     Expression, purification, crystallization and preliminary X-ray
            analysis of Escherichia coli argininosuccinate synthetase
  JOURNAL   Acta Crystallogr. D Biol. Crystallogr. 55 (Pt 12), 2028-2030 (1999)
   PUBMED   10666579
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF003779.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK05370
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..447
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..447
                     /gene="argG"
     Protein         1..447
                     /product="argininosuccinate synthase"
                     /EC_number="6.3.4.5"
                     /GO_function="GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=49767
     Region          1..446
                     /region_name="PRK05370"
                     /note="argininosuccinate synthase; Validated"
                     /db_xref="CDD:235434"
ORIGIN      
        1 mttilkhlpv gqrigiafsg gldtsaallw mrqkgavpya ytanlgqpde edydaiprra
       61 meygaenarl idcrkqlvae giaaiqcgaf hnttggltyf nttplgravt gtmlvaamke
      121 dgvniwgdgs tykgndierf yryglltnae lqiykpwldt dfidelggrh emsefmiacg
      181 fdykmsveka ystdsnmlga theakdleyl nssvkivnpi mgvkfwdesv kipaeevtvr
      241 feqghpvaln gktfsddvem mleanriggr hglgmsdqie nriieaksrg iyeapgmall
      301 hiayerlltg ihnedtieqy hahgrqlgrl lyqgrwfdsq almlrdslqr wvasqitgev
      361 tlelrrgndy silntvsenl tykperltme kgdsvfspdd rigqltmrnl ditdtreklf
      421 gyaktgllss saasgvpqve nlenkgq