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LOCUS WP_000207678 447 aa linear BCT 06-APR-2022 ACCESSION WP_000207678 VERSION WP_000207678.1 KEYWORDS RefSeq. SOURCE Enterobacteriaceae ORGANISM Enterobacteriaceae Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales. REFERENCE 1 (residues 1 to 447) AUTHORS Lemke,C.T. and Howell,P.L. TITLE The 1.6 A crystal structure of E. coli argininosuccinate synthetase suggests a conformational change during catalysis JOURNAL Structure 9 (12), 1153-1164 (2001) PUBMED 11738042 REFERENCE 2 (residues 1 to 447) AUTHORS Lemke,C., Yeung,M. and Howell,P.L. TITLE Expression, purification, crystallization and preliminary X-ray analysis of Escherichia coli argininosuccinate synthetase JOURNAL Acta Crystallogr. D Biol. Crystallogr. 55 (Pt 12), 2028-2030 (1999) PUBMED 10666579 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: NF003779.0 Evidence Source :: NCBI Protein Cluster (PRK) Source Identifier :: PRK05370 ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..447 /organism="Enterobacteriaceae" /db_xref="taxon:543" gene 1..447 /gene="argG" Protein 1..447 /product="argininosuccinate synthase" /EC_number="6.3.4.5" /GO_function="GO:0004055 - argininosuccinate synthase activity [Evidence IEA]" /GO_function="GO:0005524 - ATP binding [Evidence IEA]" /GO_function="GO:0042803 - protein homodimerization activity [Evidence IEA]" /GO_process="GO:0006526 - arginine biosynthetic process [Evidence IEA]" /calculated_mol_wt=49800 Region 1..446 /region_name="PRK05370" /note="argininosuccinate synthase; Validated" /db_xref="CDD:235434" ORIGIN 1 mttilkhlpv gqrigiafsg gldtsaallw mrqkgavpya ytanlgqpde edydaiprra 61 meygaenarl idcrkqlvae giaaiqcgaf hnttggltyf nttplgravt gtmlvaamke 121 dgvniwgdgs tykgndierf yryglltnae lqiykpwldt dfidelggrh emsefmiacg 181 fdykmsveka ystdsnmlga theakdleyl nssvkivnpi mgvkfwdesv kipaeevtvr 241 feqghpvaln gktfsddvem mleanriggr hglgmsdqie nriieaksrg iyeapgmall 301 hiayerlltg ihnedtieqy hahgrqlgrl lyqgrwfdsq almlrdslqr wvasqitgev 361 tlelrrgndy silntvsenl tykperltme kgdsvfspdd rigqltmrnl ditdtreklf 421 gyaktgllss saasgvpqme nlenkgq