MULTISPECIES: L-threonate dehydrogenase [Salmonella].

LOCUS       WP_000206958             307 aa            linear   BCT 22-OCT-2023
ACCESSION   WP_000206958
VERSION     WP_000206958.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 307)
  AUTHORS   Zhang,X., Carter,M.S., Vetting,M.W., San Francisco,B., Zhao,S.,
            Al-Obaidi,N.F., Solbiati,J.O., Thiaville,J.J., de Crecy-Lagard,V.,
            Jacobson,M.P., Almo,S.C. and Gerlt,J.A.
  TITLE     Assignment of function to a domain of unknown function: DUF1537 is
            a new kinase family in catabolic pathways for acid sugars
  JOURNAL   Proc Natl Acad Sci U S A 113 (29), E4161-E4169 (2016)
   PUBMED   27402745
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF043037.1
            Evidence Source    :: NCBIFAM
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..307
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..307
                     /gene="ltnD"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
     Protein         1..307
                     /product="L-threonate dehydrogenase"
                     /EC_number="1.1.1.411"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=31131
     Region          8..292
                     /region_name="MmsB"
                     /note="3-hydroxyisobutyrate dehydrogenase or related
                     beta-hydroxyacid dehydrogenase [Lipid transport and
                     metabolism]; COG2084"
                     /db_xref="CDD:441687"
ORIGIN      
        1 mttgtdfhvg ivglgsmgmg aarsclragl stwgadlnpq acanllaega cgaaasaref
       61 agvvdalvil vvnaaqvrqv lfgedgvahl mkpgsavmvs stissadaqe iaaaltalnl
      121 nmldapvsgg avkaaqgemt vmasgseaaf trlkpvldav asnvyrisdt pgagstvkii
      181 hqllagvhia aaaeamalaa ragipldvmy dvvthaagns wmfenrmqhv vdgdytprsa
      241 vdifvkdlgl vadtakalrf plplastaln mftsasnagy gkeddsavik ifsgitlpgv
      301 tpeepsc