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nucleoside triphosphate pyrophosphatase YhdE [Escherichia coli].


LOCUS       WP_000203107             197 aa            linear   BCT 10-JUL-2019
ACCESSION   WP_000203107
VERSION     WP_000203107.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 197)
  AUTHORS   Shen,Q., Tan,H., Xing,G.W., Zheng,J. and Jia,Z.
  TITLE     A new method to investigate the catalytic mechanism of YhdE
            pyrophosphatase by using a pyrophosphate fluorescence probe
  JOURNAL   Sci Rep 7 (1), 8169 (2017)
   PUBMED   28811554
REFERENCE   2  (residues 1 to 197)
  AUTHORS   Wang,N., Jiang,J., Li,X., Tan,H., Zheng,J., Chen,G. and Jia,Z.
  TITLE     Molecular Dynamics Simulation Studies of dTTP Binding and Catalysis
            Mediated by YhdE Dimerization
  JOURNAL   PLoS ONE 10 (8), e0134879 (2015)
   PUBMED   26252214
REFERENCE   3  (residues 1 to 197)
  AUTHORS   Tchigvintsev,A., Tchigvintsev,D., Flick,R., Popovic,A., Dong,A.,
            Xu,X., Brown,G., Lu,W., Wu,H., Cui,H., Dombrowski,L., Joo,J.C.,
            Beloglazova,N., Min,J., Savchenko,A., Caudy,A.A., Rabinowitz,J.D.,
            Murzin,A.G. and Yakunin,A.F.
  TITLE     Biochemical and structural studies of conserved Maf proteins
            revealed nucleotide pyrophosphatases with a preference for modified
            nucleotides
  JOURNAL   Chem. Biol. 20 (11), 1386-1398 (2013)
   PUBMED   24210219
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR008091
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..197
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..197
                     /gene="yhdE"
     Protein         1..197
                     /product="nucleoside triphosphate pyrophosphatase YhdE"
                     /calculated_mol_wt=21345
     Region          4..185
                     /region_name="Maf"
                     /note="7-methyl-GTP pyrophosphatase and related NTP
                     pyrophosphatases, Maf/HAM1 superfamily [Secondary
                     metabolites biosynthesis, transport and catabolism];
                     COG0424"
                     /db_xref="CDD:440193"
ORIGIN      
        1 mtslylasgs prrqellaql gvtferivtg ieeqrqpqes aqqyvvrlar ekaragvaqt
       61 akdlpvlgad tivilngevl ekprdaehaa qmlrklsgqt hqvmtavala dsrhildclv
      121 vtdvtfrtlt dediagyvas gepldkagay giqglggcfv rkingsyqav vglplvetye
      181 llsnfnalre krdkhdg