MFS transporter [Shigella flexneri].

LOCUS       WP_000202248             386 aa            linear   BCT 28-MAR-2023
ACCESSION   WP_000202248
VERSION     WP_000202248.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 386)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 386)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
REFERENCE   3  (residues 1 to 386)
  AUTHORS   Yan,N.
  TITLE     Structural advances for the major facilitator superfamily (MFS)
            transporters
  JOURNAL   Trends Biochem Sci 38 (3), 151-159 (2013)
   PUBMED   23403214
REFERENCE   4  (residues 1 to 386)
  AUTHORS   Law,C.J., Maloney,P.C. and Wang,D.N.
  TITLE     Ins and outs of major facilitator superfamily antiporters
  JOURNAL   Annu Rev Microbiol 62, 289-305 (2008)
   PUBMED   18537473
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13024447
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..386
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     Protein         1..386
                     /product="MFS transporter"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=41971
     Region          1..359
                     /region_name="MFS_YdiM_like"
                     /note="Inner membrane transport protein YdiM and similar
                     proteins of the Major Facilitator Superfamily of
                     transporters; cd17396"
                     /db_xref="CDD:340954"
     Site            order(30,80..81,83..85,88,107,110..111,114,184,187..188,
                     191..193,196,227,231,282..283,287,291,307,310..311,
                     314..315,318)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340954"
ORIGIN      
        1 mtslaekfst dnagiaylis giglgrlisi lffgvisdkf grravilmav imyllfffgi
       61 pacpnltlay glavcvgian saldtggypa lmecfpkasg savilvkamv sfgqmfypml
      121 vsymllnniw ygygliipgi lfvlitlmll kskfpsqlvd asvanelpqm nskplvwleg
      181 vssvlfgvaa fstfyvivvw mpkyamafag mseaealkti syysmgslvc vfifaallkk
      241 mvrpiwanvf nsalatitaa iiylypsplv cnagafvigf saaggilqlg vsvmseffpk
      301 skakvtsiym mmgglanfvi plitgylsni glqyiivldf tfallalita iivfsryyrv
      361 fiipendvrf gerkfstrln tikhrg