MULTISPECIES: cystathionine gamma-synthase [Salmonella].

LOCUS       WP_000197217             386 aa            linear   BCT 10-SEP-2020
ACCESSION   WP_000197217
VERSION     WP_000197217.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF005961.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK08045
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..386
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..386
                     /gene="metB"
     Protein         1..386
                     /product="cystathionine gamma-synthase"
                     /EC_number="2.5.1.48"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019346 - transsulfuration [Evidence IEA]"
                     /calculated_mol_wt=41530
     Region          1..386
                     /region_name="PRK08045"
                     /note="cystathionine gamma-synthase; Provisional"
                     /db_xref="CDD:169194"
     Site            order(29..32,34..35,46,48,74..75,77..78,101,106,109,197,
                     205,207,224,234,236..237,316)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:99738"
     Site            order(75..77,101,144,173,195,197..198,207)
                     /site_type="active"
                     /note="substrate-cofactor binding pocket [active]"
                     /db_xref="CDD:99738"
     Site            order(75..77,101,173,176,195,197..198)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]"
                     /db_xref="CDD:99738"
     Site            198
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99738"
ORIGIN      
        1 mtrkqatiav rsglnddeqy gcvvppihls stynftgfne prahdysrrg nptrdvvqra
       61 laeleggaga vltntgmsai hlvttvflkp gdllvaphdc yggsyrlfds latrgcyrvr
      121 fvdqgderal qaaleekpkl vlvespsnpl lrvvdiakic rlareagavs vvdntflspa
      181 lqnplalgad lvlhsctkyl nghsdvvagv viakdpevvt elawwannig vtggafdsyl
      241 llrglrtlvp rmelaqrnaq aivkylqtqp lvkklyhpsl penqgheiaa rqqkgfgaml
      301 sfeldgdeet lrrflgglsl ftlaeslggv eslishaatm thagmspqar asagisetll
      361 ristgiedge dliadlengf raankg