Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

fumarylacetoacetate hydrolase family protein [Escherichia coli].


LOCUS       WP_000196038             233 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_000196038
VERSION     WP_000196038.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 233)
  AUTHORS   Weiss,A.K.H., Loeffler,J.R., Liedl,K.R., Gstach,H. and
            Jansen-Durr,P.
  TITLE     The fumarylacetoacetate hydrolase (FAH) superfamily of enzymes:
            multifunctional enzymes from microbes to mitochondria
  JOURNAL   Biochem Soc Trans 46 (2), 295-309 (2018)
   PUBMED   29487229
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11415096
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..233
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..233
                     /product="fumarylacetoacetate hydrolase family protein"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /calculated_mol_wt=25760
     Region          23..233
                     /region_name="YcgM"
                     /note="2-keto-4-pentenoate
                     hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase
                     (catechol pathway) [Secondary metabolites biosynthesis,
                     transport and catabolism]; COG0179"
                     /db_xref="CDD:439949"
ORIGIN      
        1 mtqyvfepqa pvtvpvvgsd eqfpvrrvyc vgrnyaahar emgfdpdrep pfffckpada
       61 vvpvaagetl alpypaqtdn yhyeielvva igkkgsdipl ehaheyvwgy atgldmtrrd
      121 rqmemrqmgr pweigkafdl sapiaplhka rdiggidnap iwlqvngedh qrsdirhliw
      181 svneticyls gffelqpgdl iftgtpegvg pvvkgdvitg nvegltpiav kiv