aminopeptidase N [Escherichia coli].

LOCUS       WP_000193803             870 aa            linear   BCT 10-JUN-2024
ACCESSION   WP_000193803
VERSION     WP_000193803.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 870)
  AUTHORS   Chandu,D. and Nandi,D.
  TITLE     PepN is the major aminopeptidase in Escherichia coli: insights on
            substrate specificity and role during sodium-salicylate-induced
            stress
  JOURNAL   Microbiology (Reading) 149 (Pt 12), 3437-3447 (2003)
   PUBMED   14663077
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02414.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..870
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..870
                     /gene="pepN"
     Protein         1..870
                     /product="aminopeptidase N"
                     /EC_number="3.4.11.2"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /calculated_mol_wt=98741
     Region          1..870
                     /region_name="pepN"
                     /note="aminopeptidase N; Provisional; PRK14015"
                     /db_xref="CDD:237585"
     Site            order(119,121,258..264,294,297..298,301,319..320,373,376,
                     381..382)
                     /site_type="active"
                     /db_xref="CDD:341063"
ORIGIN      
        1 mtqqpqakyr hdyrapdyqi tdidltfdld aqktvvtavs qavrhgasda plclngedlk
       61 lvsvhindep wtawkeeega lvisnlperf tlkiineisp aantalegly qsgdalctqc
      121 eaegfrhity yldrpdvlar fttkiiadkt kypfllsngn rvaqgeleng rhwvqwqdpf
      181 pkpcylfalv agdfdvlrdt fttrsgreva lelyvdrgnl drapwamtsl knsmkwdeer
      241 fgleydldiy mivavdffnm gamenkglni fnskyvlart dtatdkdyld iervigheyf
      301 hnwtgnrvtc rdwfqlslke gltvfrdqef ssdlgsravn rinnvrtmrg lqfaedaspm
      361 ahpirpdmvi emnnfytltv yekgaevirm ihtllgeenf qkgmqlyfer hdgsaatcdd
      421 fvqamedasn vdlshfrrwy sqsgtpvvtv kddynpeteq ytltisqrtp atpdqaekqp
      481 lhipfaiely dnegkviplq kgghpvnsvl nvtqaeqtfv fdnvyfqpvp allcefsapv
      541 kleykwsdqq ltflmrharn dfsrwdaaqs llatyiklnv arhqqgqpls lpvhvadafr
      601 avlldekidp alaaeiltlp svnemaelfd iidpiaiaev realtrtlat eladellaiy
      661 nanyqseyrv ehediakrtl rnaclrflaf gethladvlv skqyheannm tdalaalsaa
      721 vaaqlpcrda lmqeyddkwh qdglvmdkwf ilqatspaan vletvrgllq hrsftmsnpn
      781 rirsligafa gsnpaafhae dgsgyqflve mltdlnsrnp qvasrliepl irlkrydakr
      841 qekmraaleq lkglenlsgd lyekitkala