MULTISPECIES: imidazole glycerol phosphate synthase subunit HisH

LOCUS       WP_000193246             203 aa            linear   BCT 17-JUN-2024
            [Vibrio].
ACCESSION   WP_000193246
VERSION     WP_000193246.1
KEYWORDS    RefSeq.
SOURCE      Vibrio
  ORGANISM  Vibrio
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae.
REFERENCE   1  (residues 1 to 203)
  AUTHORS   Beismann-Driemeyer,S. and Sterner,R.
  TITLE     Imidazole glycerol phosphate synthase from Thermotoga maritima.
            Quaternary structure, steady-state kinetics, and reaction mechanism
            of the bienzyme complex
  JOURNAL   J Biol Chem 276 (23), 20387-20396 (2001)
   PUBMED   11264293
REFERENCE   2  (residues 1 to 203)
  AUTHORS   Klem,T.J., Chen,Y. and Davisson,V.J.
  TITLE     Subunit interactions and glutamine utilization by Escherichia coli
            imidazole glycerol phosphate synthase
  JOURNAL   J Bacteriol 183 (3), 989-996 (2001)
   PUBMED   11208798
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01855.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..203
                     /organism="Vibrio"
                     /db_xref="taxon:662"
     gene            1..203
                     /gene="hisH"
     Protein         1..203
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /EC_number="4.3.2.10"
                     /GO_function="GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=22143
     Region          3..203
                     /region_name="hisH"
                     /note="imidazole glycerol phosphate synthase subunit HisH;
                     Provisional; PRK13170"
                     /db_xref="CDD:183877"
     Site            order(43..50,77..81,185,187)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:153219"
     Site            43..50
                     /site_type="active"
                     /note="oxyanion strand [active]"
                     /db_xref="CDD:153219"
     Site            order(79,185,187)
                     /site_type="active"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:153219"
ORIGIN      
        1 mtqnvviidt gcanissvkf aierlgyavt isrdpqvvla adklflpgvg taseamknlt
       61 erdlielvkr vekpllgicl gmqllgklse ekgqkadeiv qclglvdgev rllktgdlpl
      121 phmgwntvqv keghplfngi epdayfyfvh sfampvgdyt iaqceygqpf saaiqagnyy
      181 gvqfhperss kagarliqnf lel