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MULTISPECIES: flagellar phase variation DNA invertase Hin


LOCUS       WP_000190912             190 aa            linear   BCT 10-SEP-2020
            [Salmonella].
ACCESSION   WP_000190912
VERSION     WP_000190912.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 190)
  AUTHORS   Feng,J.A., Johnson,R.C. and Dickerson,R.E.
  TITLE     Hin recombinase bound to DNA: the origin of specificity in major
            and minor groove interactions
  JOURNAL   Science 263 (5145), 348-355 (1994)
   PUBMED   8278807
REFERENCE   2  (residues 1 to 190)
  AUTHORS   Heichman,K.A. and Johnson,R.C.
  TITLE     The Hin invertasome: protein-mediated joining of distant
            recombination sites at the enhancer
  JOURNAL   Science 249 (4968), 511-517 (1990)
   PUBMED   2166334
REFERENCE   3  (residues 1 to 190)
  AUTHORS   Silverman,M., Zieg,J., Mandel,G. and Simon,M.
  TITLE     Analysis of the functional components of the phase variation system
  JOURNAL   Cold Spring Harb. Symp. Quant. Biol. 45 Pt 1, 17-26 (1981)
   PUBMED   6271461
REFERENCE   4  (residues 1 to 190)
  AUTHORS   Simon,M., Zieg,J., Silverman,M., Mandel,G. and Doolittle,R.
  TITLE     Phase variation: evolution of a controlling element
  JOURNAL   Science 209 (4463), 1370-1374 (1980)
   PUBMED   6251543
REFERENCE   5  (residues 1 to 190)
  AUTHORS   Zieg,J. and Simon,M.
  TITLE     Analysis of the nucleotide sequence of an invertible controlling
            element
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 77 (7), 4196-4200 (1980)
   PUBMED   6933466
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR000864
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..190
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..190
                     /gene="hin"
     Protein         1..190
                     /product="flagellar phase variation DNA invertase Hin"
                     /calculated_mol_wt=21295
     Region          3..127
                     /region_name="SR_ResInv"
                     /note="Serine Recombinase (SR) family, Resolvase and
                     Invertase subfamily, catalytic domain; members contain a
                     C-terminal DNA binding domain. Serine recombinases
                     catalyze site-specific recombination of DNA molecules by a
                     concerted, four-strand cleavage and...; cd03768"
                     /db_xref="CDD:239737"
     Site            order(8,10,65..66,69)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:239737"
     Site            10
                     /site_type="active"
                     /note="catalytic nucleophile [active]"
                     /db_xref="CDD:239737"
     Site            order(64,108..109,111..112,116)
                     /site_type="other"
                     /note="Presynaptic Site I dimer interface [polypeptide
                     binding]"
                     /db_xref="CDD:239737"
     Site            order(70,75..76,104,107..108,111..112,115,118)
                     /site_type="other"
                     /note="Synaptic Antiparallel dimer interface [polypeptide
                     binding]"
                     /db_xref="CDD:239737"
     Site            order(93..95,104..105,108..109,112,116,119,123)
                     /site_type="other"
                     /note="Synaptic Flat tetramer interface [polypeptide
                     binding]"
                     /db_xref="CDD:239737"
     Site            order(93,109,112,116,119,123)
                     /site_type="other"
                     /note="Synaptic Site I dimer interface [polypeptide
                     binding]"
                     /db_xref="CDD:239737"
     Site            order(117,123..124)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:239737"
     Region          139..183
                     /region_name="HTH_7"
                     /note="Helix-turn-helix domain of resolvase; pfam02796"
                     /db_xref="CDD:397088"
     Site            order(140..142,174..175,177..179)
                     /site_type="DNA binding"
                     /note="DNA-binding interface [nucleotide binding]"
                     /db_xref="CDD:259851"
ORIGIN      
        1 matigyirvs tidqnidlqr naltsancdr ifedrisgki anrpglkral kyvnkgdtlv
       61 vwkldrlgrs vknlvalise lhergahfhs ltdsidtssa mgrfffhvms alaemereli
      121 vertlaglaa araqgrlggr prainkheqe qisrllekgh prqqlaiifg igvstlyryf
      181 pasrikkrmn