type I pantothenate kinase [Escherichia coli].

LOCUS       WP_000189379             308 aa            linear   BCT 29-APR-2021
ACCESSION   WP_000189379
VERSION     WP_000189379.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 308)
  AUTHORS   Song,W.J. and Jackowski,S.
  TITLE     Kinetics and regulation of pantothenate kinase from Escherichia
            coli
  JOURNAL   J Biol Chem 269 (43), 27051-27058 (1994)
   PUBMED   7929447
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00554.2
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..308
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..308
                     /gene="coaA"
     Protein         1..308
                     /product="type I pantothenate kinase"
                     /EC_number="2.7.1.33"
                     /GO_function="GO:0004594 - pantothenate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=35298
     Region          19..308
                     /region_name="panK_bact"
                     /note="pantothenate kinase, bacterial type; TIGR00554"
                     /db_xref="CDD:273134"
     Site            order(90,93..96,231,235,295,299)
                     /site_type="other"
                     /note="ATP-binding site [chemical binding]"
                     /db_xref="CDD:238983"
     Site            order(93..94,98,169,235,239,299)
                     /site_type="other"
                     /note="CoA-binding site [chemical binding]"
                     /db_xref="CDD:238983"
     Site            order(94,191)
                     /site_type="other"
                     /note="Mg2+-binding site [ion binding]"
                     /db_xref="CDD:238983"
ORIGIN      
        1 mtpylqfdrn qwaalrdsvp mtlsedeiar lkginedlsl eevaeiylpl srllnfyiss
       61 nlrrqavleq flgtngqrip yiisiagsva vgksttarvl qallsrwpeh rrvelittdg
      121 flhpnqvlke rglmkkkgfp esydmhrlvk fvsdlksgvp nvtapvyshl iydvipdgdk
      181 tvvqpdilil eglnvlqsgm dyphdphhvf vsdfvdfsiy vdapedllqt wyinrflkfr
      241 egaftdpdsy fhnyakltke eaiktamtlw keinwlnlkq nilptreras liltksanha
      301 veevrlrk