macrolide ABC transporter ATP-binding protein/permease MacB

LOCUS       WP_000188174             648 aa            linear   BCT 12-JUN-2023
            [Escherichia coli].
ACCESSION   WP_000188174
VERSION     WP_000188174.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 648)
  AUTHORS   Fitzpatrick,A.W.P., Llabres,S., Neuberger,A., Blaza,J.N., Bai,X.C.,
            Okada,U., Murakami,S., van Veen,H.W., Zachariae,U., Scheres,S.H.W.,
            Luisi,B.F. and Du,D.
  TITLE     Structure of the MacAB-TolC ABC-type tripartite multidrug efflux
            pump
  JOURNAL   Nat Microbiol 2, 17070 (2017)
   PUBMED   28504659
  REMARK    Publication Status: Online-Only
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007826.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10535
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..648
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..648
                     /gene="macB"
     Protein         1..648
                     /product="macrolide ABC transporter ATP-binding
                     protein/permease MacB"
                     /GO_component="GO:1990195 - macrolide transmembrane
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /calculated_mol_wt=70546
     Region          1..648
                     /region_name="PRK10535"
                     /note="macrolide ABC transporter ATP-binding
                     protein/permease MacB"
                     /db_xref="CDD:182528"
ORIGIN      
        1 mtpllelkdi rrsypagdeq vevlkgitld iyagemvaiv gasgsgkstl mnilgcldka
       61 tsgtyrvagq dvatldadal aqlrrehfgf ifqryhllsh ltaeqnvevp avyaglerkq
      121 rllraqellq rlgledrtey ypaqlsggqq qrvsiaralm nggqvilade ptgaldshsg
      181 eevmailhql rdrghtviiv thdpqvaaqa ervieirdge ivrnppaiek vnvaggtepv
      241 vntasgwrqf vsgfnealtm awralaankm rtlltmlgii igiasvvsiv vvgdaakqmv
      301 ladirsigtn tidvypgkdf gdddpqyqqa lkyddliaiq kqpwvasatp avsqnlrlry
      361 nnvdvaasan gvsgdyfnvy gmtfsegntf nqeqlngraq vvvldsntrr qlfphkadvv
      421 gevilvgnmp arvigvaeek qsmfgsskvl rvwlpystms grvmgqswln sitvrvkegf
      481 dsaeaeqqlt rllslrhgkk dfftwnmdgv lktvekttrt lqlfmtlvav islvvggigv
      541 mnimlvsvte rtreigirma vgarasdvlq qflieavlvc lvggalgitl slliaftlql
      601 flpgweigfs plalllaflc stvtgilfgw lparnaarld pvdalare