anaerobic ribonucleoside-triphosphate reductase [Escherichia coli].

LOCUS       WP_000187775             712 aa            linear   BCT 16-JUN-2019
ACCESSION   WP_000187775
VERSION     WP_000187775.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF006732.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK09263
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..712
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..712
                     /gene="nrdD"
     Protein         1..712
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /EC_number="1.17.4.2"
                     /GO_function="GO:0008998 - ribonucleoside-triphosphate
                     reductase activity [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /calculated_mol_wt=79906
     Region          1..711
                     /region_name="PRK09263"
                     /note="anaerobic ribonucleoside triphosphate reductase;
                     Provisional"
                     /db_xref="CDD:236436"
     Site            order(160,162..163,195..199,203,206..207,210,242,546..549,
                     552)
                     /site_type="active"
                     /note="effector binding site [active]"
                     /db_xref="CDD:153084"
     Site            order(175,222,290,383..384,407,544,547)
                     /site_type="active"
                     /db_xref="CDD:153084"
     Site            order(644,647,662,665)
                     /site_type="other"
                     /note="Zn binding site [ion binding]"
                     /db_xref="CDD:153084"
     Site            678..682
                     /site_type="active"
                     /note="glycine loop [active]"
                     /db_xref="CDD:153084"
ORIGIN      
        1 mtphvmkrdg ckvpfkseri keailraaka aevddadyca tvaavvseqm qgrnqvdine
       61 iqtavenqlm sgpykqlara yieyrhdrdi erekrgrlnq eirglveqtn asllnenank
      121 dskviptqrd llagivakhy arqhllprdv vqahergdih yhdldyspff pmfncmlidl
      181 kgmltqgfkm gnaeieppks istatavtaq iiaqvashiy ggttinride vlapfvtasy
      241 nkhrktaeew nipdaegyan srtikecyda fqsleyevnt lhtangqtpf vtfgfglgts
      301 wesrliqesi lrnriaglgk nrktavfpkl vfairdglnh kkgdpnydik qlalecaskr
      361 mypdilnydq vvkvtgsfkt pmgcrsflgv wenengeqih dgrnnlgvis lnlprialea
      421 kgdeatfwkl lderlvlark almtriarle gvkarvapil ymegacgvrl nadddiseif
      481 kngrasislg yigihetina lfggehvydn eqlrakgiai verlrqavdq wkeetgygfs
      541 lystpsenlc drfcrldtae fgvvpgvtdk gyytnsfhld vekkvnpydk idfeapyppl
      601 anggficyge ypniqhnlka ledvwdysyq hvpyygtntp idecyecgft gefectskgf
      661 tcpkcgnhda srvsvtrrvc gylgspdarp fnagkqeevk rrvkhlgngq ig