MULTISPECIES: DNA-binding transcriptional regulator NagC

LOCUS       WP_000187594             406 aa            linear   BCT 14-JAN-2025
            [Enterobacteriaceae].
ACCESSION   WP_000187594
VERSION     WP_000187594.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 406)
  AUTHORS   Pennetier,C., Dominguez-Ramirez,L. and Plumbridge,J.
  TITLE     Different regions of Mlc and NagC, homologous transcriptional
            repressors controlling expression of the glucose and
            N-acetylglucosamine phosphotransferase systems in Escherichia coli,
            are required for inducer signal recognition
  JOURNAL   Mol Microbiol 67 (2), 364-377 (2008)
   PUBMED   18067539
REFERENCE   2  (residues 1 to 406)
  AUTHORS   Plumbridge,J.
  TITLE     DNA binding sites for the Mlc and NagC proteins: regulation of
            nagE, encoding the N-acetylglucosamine-specific transporter in
            Escherichia coli
  JOURNAL   Nucleic Acids Res 29 (2), 506-514 (2001)
   PUBMED   11139621
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF047937.1
            Evidence Source    :: NCBIFAM
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..406
                     /gene="nagC"
                     /gene_synonym="nagR"
     Protein         1..406
                     /product="DNA-binding transcriptional regulator NagC"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /calculated_mol_wt=44410
     Region          25..77
                     /region_name="HTH_ARSR"
                     /note="Arsenical Resistance Operon Repressor and similar
                     prokaryotic, metal regulated homodimeric repressors. ARSR
                     subfamily of helix-turn-helix bacterial transcription
                     regulatory proteins (winged helix topology). Includes
                     several proteins that appear to...; cl46857"
                     /db_xref="CDD:481197"
     Region          86..400
                     /region_name="ASKHA_ATPase_ROK_NagC"
                     /note="ATPase-like domain of N-acetylglucosamine repressor
                     (NagC) and similar proteins; cd24075"
                     /db_xref="CDD:466925"
ORIGIN      
        1 mtpggqaqig nvdlvkqlns aavyrlidqy gpisriqiae qsqlapasvt kitrqlierg
       61 likevdqqas tggrraisiv tetrnfhaig vrlgrhdati tlfdlsskvl aeehyplper
      121 tqqtlehall naiaqfidsy qrklreliai svilpglvdp dsgkihymph iqvenwglve
      181 aleerfkvtc fvghdirsla laehyfgasq dcedsilvrv hrgtgagiis ngrifigrng
      241 nvgeighiqv eplgerchcg nfgcletiaa naaieqrvln llkqgyqsrv plddctikti
      301 ckaankgdsl asevieyvgr hlgktiaiai nlfnpqkivi ageiteadkv llpaiescin
      361 tqalkafrtn lpvvrseldh rsaigafalv kramlngill qhllen