Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: bifunctional nicotinamidase/pyrazinamidase


LOCUS       WP_000184708             218 aa            linear   BCT 08-NOV-2019
            [Salmonella].
ACCESSION   WP_000184708
VERSION     WP_000184708.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 218)
  AUTHORS   Wang,X., Liu,B., Dou,Y., Fan,H., Wang,S., Li,T., Ding,C. and Yu,S.
  TITLE     The Riemerella anatipestifer AS87_01735 Gene Encodes Nicotinamidase
            PncA, an Important Virulence Factor
  JOURNAL   Appl. Environ. Microbiol. 82 (19), 5815-5823 (2016)
   PUBMED   27451449
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008623.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11609
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..218
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..218
                     /gene="pncA"
     Protein         1..218
                     /product="bifunctional nicotinamidase/pyrazinamidase"
                     /EC_number="3.5.1.-"
                     /EC_number="3.5.1.19"
                     /calculated_mol_wt=23810
     Region          2..213
                     /region_name="PRK11609"
                     /note="bifunctional nicotinamidase/pyrazinamidase"
                     /db_xref="CDD:183228"
     Site            order(10,111,156)
                     /site_type="active"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:238493"
     Site            order(52,54,86)
                     /site_type="metal-binding"
                     /note="metal binding site [ion binding]"
                     /db_xref="CDD:238493"
     Site            151..152
                     /site_type="active"
                     /note="conserved cis-peptide bond [active]"
                     /db_xref="CDD:238493"
ORIGIN      
        1 mtnralllvd lqndfcagga lavaegdsti dianalidwc qprqipvlas qdwhpaqhgs
       61 fasqhqaepy sqgkldglpq tlwpdhcvqh tdgaalhpll nqhaidaciy kgenplidsy
      121 saffdnehrq kttldtwlre hdvtelivmg latdycvkft vldalelgya vnvitdgcrg
      181 vnihpqdsah afmemasaga tlytladwee tqgqavar