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succinylglutamate-semialdehyde dehydrogenase [Escherichia coli].


LOCUS       WP_000177232             492 aa            linear   BCT 01-JUL-2024
ACCESSION   WP_000177232
VERSION     WP_000177232.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR03240.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..492
                     /gene="astD"
     Protein         1..492
                     /product="succinylglutamate-semialdehyde dehydrogenase"
                     /EC_number="1.2.1.71"
                     /GO_function="GO:0043824 - succinylglutamate-semialdehyde
                     dehydrogenase activity [Evidence IEA]"
                     /GO_process="GO:0006527 - arginine catabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=52854
     Region          3..486
                     /region_name="arg_catab_astD"
                     /note="succinylglutamate-semialdehyde dehydrogenase;
                     TIGR03240"
                     /db_xref="CDD:274486"
     Site            order(141..145,153,168,170..171,218..221,224,227..228,
                     243..245,277,375,377,403,442)
                     /site_type="other"
                     /note="NAD(P) binding site [chemical binding]"
                     /db_xref="CDD:143414"
     Site            order(145,243,274,277)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143414"
ORIGIN      
        1 mtlwingdwi tgqgasrvkr npvsgevlwq gndadaaqvg qacraaraaf prwarlsfae
       61 rqavverfag llernkgelt aiiaretgkp rweaatelta minkiaisik ayhvrtgeqr
      121 sempdgaasl rhrphgvlav fgpynfpghl pnghivpall agntiifkps eltpwsgeav
      181 mrlwqqaglp pgvlnlvqgg cetgqalsal edldgllftg santgyqlhr qlsgqpekil
      241 alemggnnpl iidevadida avhltiqsaf vtagqrctca rrvllksgaq gdaflarlva
      301 vsqrltpgnw ddepqpfigg liseqaaqqv ftawqqleam ggrtllaprl lqagtslltp
      361 giiemtgvag vpdeevfgpl lrvwrydsfe eairmanntr fglscglvsp erekfdqlll
      421 earagivnwn kpltgaasta pfggigasgn hrpsawyaad ycawpmasle sdsltlpatl
      481 npgldfsdev vr