MFS transporter [Escherichia coli].

LOCUS       WP_000171064             375 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_000171064
VERSION     WP_000171064.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 375)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 375)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
REFERENCE   3  (residues 1 to 375)
  AUTHORS   Yan,N.
  TITLE     Structural advances for the major facilitator superfamily (MFS)
            transporters
  JOURNAL   Trends Biochem Sci 38 (3), 151-159 (2013)
   PUBMED   23403214
REFERENCE   4  (residues 1 to 375)
  AUTHORS   Pao,S.S., Paulsen,I.T. and Saier,M.H. Jr.
  TITLE     Major facilitator superfamily
  JOURNAL   Microbiol Mol Biol Rev 62 (1), 1-34 (1998)
   PUBMED   9529885
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11457990
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..375
                     /product="MFS transporter"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=39316
     Region          1..371
                     /region_name="nepI"
                     /note="purine ribonucleoside efflux pump NepI; PRK10213"
                     /db_xref="CDD:182309"
ORIGIN      
        1 mtlcvfvlia sefmpvsllt piardlgvte glagrgiais galavltslt lstlagkmnr
       61 kflllgmtvl mavsgliial atsylmymvg ramigvaigg fwsmsaatai rlvpqhqvtr
      121 alaifnagna latvvaaplg sylgatvgwr gaflclvpma vvafiwqcis lpsmdanksh
      181 tscgavfrlf srrmvvvgmi acglffmgqf alftyvrpfl esvtrvnslg lslilliigv
      241 agfigtlvvs iflnrkcypt lmaipglmav iaiglmltgh hvwmvslllg lwgmlataap
      301 tgwwtwiart lpdnaeaggg lmvaviqlsi algstaggiv fdrlgwqstf amssvlllca
      361 gvltfvtarq kagal