MULTISPECIES: MFS transporter [Salmonella].

LOCUS       WP_000165758             394 aa            linear   BCT 22-JUL-2024
ACCESSION   WP_000165758
VERSION     WP_000165758.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 394)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 394)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13023516
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..394
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     Protein         1..394
                     /product="MFS transporter"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=41394
     Region          13..384
                     /region_name="MFS_NepI_like"
                     /note="Purine ribonucleoside efflux pump NepI and similar
                     transporters of the Major Facilitator Superfamily;
                     cd17324"
                     /db_xref="CDD:340882"
     Site            order(23..24,27..28,31,63,113,115..117,120,140,143..144,
                     147,220,223..224,227..229,232,260,264,314..315,319,323,
                     338,341..342,345..346,349)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340882"
ORIGIN      
        1 mtkpthelsp alivlmsvat glavasnyya qplldtiahh fslsassagf ivtaaqlgya
       61 agllflvplg dmferrtliv smtllaaggm litassqsls mmilgtaltg lfsvvaqilv
      121 plaatlatpa trgkvvgtim sglllgilla rtvagllanl ggwrtvfwva salmalmava
      181 lwrglpklks dthlnypqll gsvfslfihd kllrtrallg cltfanfsil wtsmafllaa
      241 ppfsysegmi glfglagaag algarpaggf adkgkshltt tfglllllls wlaiwlghts
      301 vlaliigilv ldltvqgvhi tnqtviyrlh pdarnrltag ymtsyfigga agslisasaw
      361 qhagwagvcl agvtvallnl lvwwrgfhrq eavn