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succinate-semialdehyde dehydrogenase [Escherichia coli].


LOCUS       WP_000156618             462 aa            linear   BCT 18-JAN-2020
ACCESSION   WP_000156618
VERSION     WP_000156618.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF010575.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK13968
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..462
                     /gene="sad"
     Protein         1..462
                     /product="succinate-semialdehyde dehydrogenase"
                     /EC_number="1.2.1.24"
                     /GO_function="GO:0004030 - aldehyde dehydrogenase
                     [NAD(P)+] activity [Evidence IEA]"
                     /calculated_mol_wt=49673
     Region          1..462
                     /region_name="PRK13968"
                     /note="putative succinate semialdehyde dehydrogenase;
                     Provisional"
                     /db_xref="CDD:184426"
     Site            order(133..137,145,160,162..163,210..213,216,219..220,
                     234..236,268,365,367,393,431)
                     /site_type="other"
                     /note="NAD(P) binding site [chemical binding]"
                     /db_xref="CDD:143418"
     Site            order(137,234,265,268)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143418"
ORIGIN      
        1 mtitpathai sinpatgeql svlpwagadd ienalqlaaa gfrdwretni dyraeklrdi
       61 gkalrarsee maqmitremg kpinqaraev aksanlcdwy aehgpamlka eptlvenqqa
      121 vieyrplgti laimpwnfpl wqvmrgavpi ilagngyllk hapnvmgcaq liaqvfkdag
      181 ipqgvygwln adndgvtqmi kdsriaaitv tgsvragaai gaqagaalkk cvlelggsdp
      241 fivlndadle lavkaavagr yqntgqvcaa akrfiieegi asafterfva aaaalkmddp
      301 rdeenalgpm arfdlrdelh hqvektlaqg arlllggekm agagnyyppt vlanvtpemt
      361 afreemfgpv aaitiakdae halelandse fglsatiftt detqarqmaa rlecggvfin
      421 gycasdarva fggvkksgfg relshfglhe fcniqtvwkd ri