MULTISPECIES: type II toxin-antitoxin system toxin mRNA

LOCUS       WP_000155570             357 aa            linear   BCT 11-FEB-2021
            endoribonuclease RnlA [Enterobacteriaceae].
ACCESSION   WP_000155570
VERSION     WP_000155570.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 357)
  AUTHORS   Wei,Y., Gao,Z.Q., Otsuka,Y., Naka,K., Yonesaki,T., Zhang,H. and
            Dong,Y.H.
  TITLE     Structure-function studies of Escherichia coli RnlA reveal a novel
            toxin structure involved in bacteriophage resistance
  JOURNAL   Mol Microbiol 90 (5), 956-965 (2013)
   PUBMED   24112600
REFERENCE   2  (residues 1 to 357)
  AUTHORS   Otsuka,Y. and Yonesaki,T.
  TITLE     Dmd of bacteriophage T4 functions as an antitoxin against
            Escherichia coli LsoA and RnlA toxins
  JOURNAL   Mol Microbiol 83 (4), 669-681 (2012)
   PUBMED   22403819
REFERENCE   3  (residues 1 to 357)
  AUTHORS   Koga,M., Otsuka,Y., Lemire,S. and Yonesaki,T.
  TITLE     Escherichia coli rnlA and rnlB compose a novel toxin-antitoxin
            system
  JOURNAL   Genetics 187 (1), 123-130 (2011)
   PUBMED   20980243
REFERENCE   4  (residues 1 to 357)
  AUTHORS   Otsuka,Y., Miki,K., Koga,M., Katayama,N., Morimoto,W., Takahashi,Y.
            and Yonesaki,T.
  TITLE     IscR regulates RNase LS activity by repressing rnlA transcription
  JOURNAL   Genetics 185 (3), 823-830 (2010)
   PUBMED   20421606
REFERENCE   5  (residues 1 to 357)
  AUTHORS   Iwamoto,A., Lemire,S. and Yonesaki,T.
  TITLE     Post-transcriptional control of Crp-cAMP by RNase LS in Escherichia
            coli
  JOURNAL   Mol Microbiol 70 (6), 1570-1578 (2008)
   PUBMED   19019153
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011257
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..357
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..357
                     /gene="rnlA"
     Protein         1..357
                     /product="type II toxin-antitoxin system toxin mRNA
                     endoribonuclease RnlA"
                     /EC_number="3.1.26.-"
                     /calculated_mol_wt=39930
     Region          7..97
                     /region_name="RNLA_N_1"
                     /note="N-terminal repeat domain of toxin RnlA; first out
                     of two repeats; cd14794"
                     /db_xref="CDD:269817"
     Site            order(13..14,36,42..44,62)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:269817"
     Region          99..184
                     /region_name="RNLA_N_2"
                     /note="N-terminal repeat domain of toxin RnlA; second out
                     of two repeats; cd14795"
                     /db_xref="CDD:269818"
     Site            order(126,129..130,132..134,144)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:269818"
     Region          203..325
                     /region_name="RnlA-toxin_DBD"
                     /note="RNase LS, bacterial toxin DBD domain; pfam19034"
                     /db_xref="CDD:408804"
ORIGIN      
        1 mtirsyknln lvranietes rqfienknys iqsigpmpgs raglrvvftr pgvnlatvdi
       61 fyngdgstti qyltganrsl gqeladhlfe tinpaefeqv nmvlqgfvet svlpvlelsa
      121 deshiefreh srnahtvvwk iistsyqdel tvslhittgk lqiqgrplsc yrvftfnlaa
      181 lldlqglekv lirqedgkan ivqqevarty lqtvmadayp hlhvtaekll vsglcvklaa
      241 pdlpdycmll ypelrtiegv lkskmsglgm pvqqpagfgt yfdkpaahyi lkpqfaatlr
      301 peqiniista ytffnverhs lfhmetvvda srmisdmarl mgkatrawgi ikdlyiv