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MULTISPECIES: UDP-N-acetylmuramate dehydrogenase [Salmonella].


LOCUS       WP_000149795             342 aa            linear   BCT 11-DEC-2019
ACCESSION   WP_000149795
VERSION     WP_000149795.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 342)
  AUTHORS   El Zoeiby,A., Sanschagrin,F. and Levesque,R.C.
  TITLE     Structure and function of the Mur enzymes: development of novel
            inhibitors
  JOURNAL   Mol. Microbiol. 47 (1), 1-12 (2003)
   PUBMED   12492849
REFERENCE   2  (residues 1 to 342)
  AUTHORS   Benson,T.E., Walsh,C.T. and Hogle,J.M.
  TITLE     X-ray crystal structures of the S229A mutant and wild-type MurB in
            the presence of the substrate enolpyruvyl-UDP-N-acetylglucosamine
            at 1.8-A resolution
  JOURNAL   Biochemistry 36 (4), 806-811 (1997)
   PUBMED   9020778
REFERENCE   3  (residues 1 to 342)
  AUTHORS   Benson,T.E., Walsh,C.T. and Hogle,J.M.
  TITLE     The structure of the substrate-free form of MurB, an essential
            enzyme for the synthesis of bacterial cell walls
  JOURNAL   Structure 4 (1), 47-54 (1996)
   PUBMED   8805513
REFERENCE   4  (residues 1 to 342)
  AUTHORS   Benson,T.E., Walsh,C.T. and Hogle,J.M.
  TITLE     Crystallization and preliminary X-ray crystallographic studies of
            UDP-N-acetylenolpyruvylglucosamine reductase
  JOURNAL   Protein Sci. 3 (7), 1125-1127 (1994)
   PUBMED   7920261
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF000755.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK00046
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..342
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..342
                     /gene="murB"
     Protein         1..342
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /EC_number="1.3.1.98"
                     /GO_function="GO:0008762 - UDP-N-acetylmuramate
                     dehydrogenase activity [Evidence IEA]"
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /calculated_mol_wt=37516
     Region          1..329
                     /region_name="murB"
                     /note="UDP-N-acetylmuramate dehydrogenase; PRK00046"
                     /db_xref="CDD:234593"
ORIGIN      
        1 mthslkpwnt fgidhcakhi vcaeneqqll sawqqatreg lpvmilgegs nvlflenyag
       61 tvilnrlkgi evnetadawh lhvgagenwh qlvryaldnn mpglenlali pgcvgsspiq
      121 nigaygvelq rvcdyvdcve letgkrlrls aaecrfgyrd sifkneyqdr vaivavglrl
      181 skqwqpvlty gdltcldpkt vtaqqvfdav chmrttklpd pkvngnagsf fknpvvaadi
      241 amellerfpn aphypqadgs vklaagwlid qcqlkgvtig gaavhrqqal vlinandats
      301 kdvvalahhv rqkvgekfnv wlepevrfig rsgevnaves ia