MULTISPECIES: MFS transporter [Shigella].

LOCUS       WP_000147685             469 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_000147685
VERSION     WP_000147685.1
KEYWORDS    RefSeq.
SOURCE      Shigella
  ORGANISM  Shigella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 469)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 469)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 469)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13022776
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Shigella"
                     /db_xref="taxon:620"
     Protein         1..469
                     /product="MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=50705
     Region          45..443
                     /region_name="MFS_SV2_like"
                     /note="Metazoan Synaptic vesicle glycoprotein 2 (SV2) and
                     related small molecule transporters of the Major
                     Facilitator Superfamily; cd17316"
                     /db_xref="CDD:340874"
     Site            order(55..56,59..60,63,95,145..146,148..150,153,173,
                     176..177,180,280,283..284,287..289,292,317,321,371..372,
                     376,380,396,399..400,403..404,407)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340874"
ORIGIN      
        1 mtgrclfgfs gekpfllpdn egvkmntspv rmddlplnrf hcriatltfg ahltdgyvlg
       61 vigyaiiqlt pamqltpfma gmiggsallg lflgslvlgw isdhigrqki ftfsfllitl
      121 asflqffatt pehliglril igiglggdys vghtllaefs prrhrgillg afsvvwtvgy
      181 vlasiaghhf isenpeawrw llasaalpal litllrwgtp esprwllcqg rfaeahaivh
      241 ryfgphvllg devvtathkh iktlfssryw rrtafnsvff vclvipwfvi ytwlptiaqt
      301 igledaltas lmlnallivg allglvlthl lahrkfllgs flllaatlvv maclpsgssl
      361 tlllfvlfst tisavsnlvg ilpaesfptd irslgvgfat amsrlgaavs tgllpwvlaq
      421 wgmqvtllll atvllvgfvv twlwapetka lplvaagnvg ganehsvsv