EAL domain-containing protein [Escherichia coli].

LOCUS       WP_000146388             362 aa            linear   BCT 01-MAR-2025
ACCESSION   WP_000146388
VERSION     WP_000146388.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 362)
  AUTHORS   Galperin,M.Y., Nikolskaya,A.N. and Koonin,E.V.
  TITLE     Novel domains of the prokaryotic two-component signal transduction
            systems
  JOURNAL   FEMS Microbiol Lett 203 (1), 11-21 (2001)
   PUBMED   11557134
  REMARK    Erratum:[FEMS Microbiol Lett 2001 Oct 16;204(1):213-4]
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF012772.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF00563.25
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..362
                     /product="EAL domain-containing protein"
                     /calculated_mol_wt=40443
     Region          26..80
                     /region_name="LuxR_C_like"
                     /note="C-terminal DNA-binding domain of LuxR-like
                     proteins. This domain contains a helix-turn-helix motif
                     and binds DNA. Proteins belonging to this group are
                     response regulators; some act as transcriptional
                     activators, others as transcriptional repressors. Many...;
                     cd06170"
                     /db_xref="CDD:99777"
     Site            order(26..28,41..43,51..52,54..55,57..61,72)
                     /site_type="DNA binding"
                     /note="DNA binding residues [nucleotide binding]"
                     /db_xref="CDD:99777"
     Site            order(37,39,41,72..74,77,80)
                     /site_type="other"
                     /note="dimerization interface [polypeptide binding]"
                     /db_xref="CDD:99777"
     Region          110..350
                     /region_name="EAL"
                     /note="Putative diguanylate phosphodiesterase; smart00052"
                     /db_xref="CDD:214491"
ORIGIN      
        1 mashdlsvfl eefgatvnlt lpgivseker lllkllmegm svteisqyrn rsaktishqk
       61 kqlyeklgiq sditfwrdif fqyhpqvisg tgnknnfyip dnrchhivtp eaislalenh
      121 efkpwiqpvf caqtgvltgc evlvrwehpq tgiippdqfi plaessgliv imtrqlmkqt
      181 adilmpvkhl lpdnfhigin vsagcflaag fekeclnlvk klgndkiklv lelternpip
      241 vtpearaifd slhqhnitfa lddfgtgyat yrylqafpvd fikidksfvq magvdeisgh
      301 ivdnivelar kpglsivaeg vetqeqadlm igkgvhflqg ylysppvpgn kfisewvmka
      361 gg