galactose/proton symporter [Shigella flexneri].

LOCUS       WP_000142589             451 aa            linear   BCT 10-FEB-2020
ACCESSION   WP_000142589
VERSION     WP_000142589.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 451)
  AUTHORS   Patching,S.G., Psakis,G., Baldwin,S.A., Baldwin,J., Henderson,P.J.
            and Middleton,D.A.
  TITLE     Relative substrate affinities of wild-type and mutant forms of the
            Escherichia coli sugar transporter GalP determined by solid-state
            NMR
  JOURNAL   Mol. Membr. Biol. 25 (6-7), 474-484 (2008)
   PUBMED   18798051
REFERENCE   2  (residues 1 to 451)
  AUTHORS   Cairns,M.T., McDonald,T.P., Horne,P., Henderson,P.J. and
            Baldwin,S.A.
  TITLE     Cytochalasin B as a probe of protein structure and substrate
            recognition by the galactose/H+ transporter of Escherichia coli
  JOURNAL   J. Biol. Chem. 266 (13), 8176-8183 (1991)
   PUBMED   1850739
REFERENCE   3  (residues 1 to 451)
  AUTHORS   Macpherson,A.J., Jones-Mortimer,M.C., Horne,P. and Henderson,P.J.
  TITLE     Identification of the GalP galactose transport protein of
            Escherichia coli
  JOURNAL   J. Biol. Chem. 258 (7), 4390-4396 (1983)
   PUBMED   6300086
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011164
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     gene            1..451
                     /gene="galP"
     Protein         1..451
                     /product="galactose/proton symporter"
                     /calculated_mol_wt=49465
     Region          1..434
                     /region_name="SP"
                     /note="MFS transporter, sugar porter (SP) family;
                     TIGR00879"
                     /db_xref="CDD:273317"
     Site            order(16,20,134,137..138,141,249..250,254..255,258..259,
                     287,349..350,353..354,358,381..382,385)
                     /site_type="other"
                     /note="chemical substrate binding pocket [chemical
                     binding]"
                     /db_xref="CDD:340873"
ORIGIN      
        1 mtffvcflaa lagllfgldi gviagalpfi adefqitsht qewvvssmmf gaavgavgig
       61 wlsfklgrkk slmigailfv agslfsaaap nvevlilsrv llglavgvas ytaplylsei
      121 apekirgsmi smyqlmitig ilgaylsdta fsytgawrwm lgviiipail lligvfflpd
      181 sprwfaakrr fvdaervllr lrdtsaeakr eldeireslq vkqsgwalfk ensnfrravf
      241 lgvllqvmqq ftgmnvimyy apkifelagy tntteqmwgt vivgltnvla tfiaiglvdr
      301 wgrkptltlg flvmaagmgv lgtmmhigih spsaqyfaia mllmfivgfa msagpliwvl
      361 cseiqplkgr dfgitcstat nwianmivga tfltmlntlg nantfwvyaa lnvlfilltl
      421 wlvpetkhvs lehiernlmk grklreigah d