MULTISPECIES: glutamine-hydrolyzing GMP synthase

LOCUS       WP_000138270             525 aa            linear   BCT 16-DEC-2020
            [Enterobacteriaceae].
ACCESSION   WP_000138270
VERSION     WP_000138270.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 525)
  AUTHORS   Tesmer,J.J., Klem,T.J., Deras,M.L., Davisson,V.J. and Smith,J.L.
  TITLE     The crystal structure of GMP synthetase reveals a novel catalytic
            triad and is a structural paradigm for two enzyme families
  JOURNAL   Nat. Struct. Biol. 3 (1), 74-86 (1996)
   PUBMED   8548458
REFERENCE   2  (residues 1 to 525)
  AUTHORS   Tesmer,J.J., Stemmler,T.L., Penner-Hahn,J.E., Davisson,V.J. and
            Smith,J.L.
  TITLE     Preliminary X-ray analysis of Escherichia coli GMP synthetase:
            determination of anomalous scattering factors for a cysteinyl
            mercury derivative
  JOURNAL   Proteins 18 (4), 394-403 (1994)
   PUBMED   8208731
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF000848.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK00074
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..525
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..525
                     /gene="guaA"
     Protein         1..525
                     /product="glutamine-hydrolyzing GMP synthase"
                     /EC_number="6.3.5.2"
                     /GO_function="GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016462 - pyrophosphatase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=58548
     Region          5..525
                     /region_name="guaA"
                     /note="GMP synthase; Reviewed; PRK00074"
                     /db_xref="CDD:234614"
ORIGIN      
        1 mtenihkhri lildfgsqyt qlvarrvrel gvycelwawd vteaqirdfn psgiilsggp
       61 estteenspr apqyvfeagv pvfgvcygmq tmamqlgghv easnerefgy aqvevvndsa
      121 lvrgiedalt adgkplldvw mshgdkvtai psdfitvast escpfaiman eekrfygvqf
      181 hpevthtrqg mrmlerfvrd icqcealwtp akiiddavar ireqvgddkv ilglsggvds
      241 svtamllhra igknltcvfv dngllrlnea eqvldmfgdh fglnivhvpa edrflsalag
      301 endpeakrki igrvfvevfd eealkledvk wlaqgtiypd viesaasatg kahvikshhn
      361 vgglpkemkm glveplkelf kdevrkigle lglpydmlyr hpfpgpglgv rvlgevkkey
      421 cdllrradai fieelrkadl ydkvsqaftv flpvrsvgvm gdgrkydwvv slravetidf
      481 mtahwahlpy dflgrvsnri inevngisrv vydisgkppa tiewe