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MULTISPECIES: tyrosine-protein kinase Wzc [Salmonella].


LOCUS       WP_000136405             719 aa            linear   BCT 10-SEP-2020
ACCESSION   WP_000136405
VERSION     WP_000136405.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 719)
  AUTHORS   Collins,R.F., Beis,K., Dong,C., Botting,C.H., McDonnell,C.,
            Ford,R.C., Clarke,B.R., Whitfield,C. and Naismith,J.H.
  TITLE     The 3D structure of a periplasm-spanning platform required for
            assembly of group 1 capsular polysaccharides in Escherichia coli
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 104 (7), 2390-2395 (2007)
   PUBMED   17283336
REFERENCE   2  (residues 1 to 719)
  AUTHORS   Grangeasse,C., Obadia,B., Mijakovic,I., Deutscher,J., Cozzone,A.J.
            and Doublet,P.
  TITLE     Autophosphorylation of the Escherichia coli protein kinase Wzc
            regulates tyrosine phosphorylation of Ugd, a UDP-glucose
            dehydrogenase
  JOURNAL   J. Biol. Chem. 278 (41), 39323-39329 (2003)
   PUBMED   12851388
REFERENCE   3  (residues 1 to 719)
  AUTHORS   Nakar,D. and Gutnick,D.L.
  TITLE     Involvement of a protein tyrosine kinase in production of the
            polymeric bioemulsifier emulsan from the oil-degrading strain
            Acinetobacter lwoffii RAG-1
  JOURNAL   J. Bacteriol. 185 (3), 1001-1009 (2003)
   PUBMED   12533476
REFERENCE   4  (residues 1 to 719)
  AUTHORS   Paiment,A., Hocking,J. and Whitfield,C.
  TITLE     Impact of phosphorylation of specific residues in the tyrosine
            autokinase, Wzc, on its activity in assembly of group 1 capsules in
            Escherichia coli
  JOURNAL   J. Bacteriol. 184 (23), 6437-6447 (2002)
   PUBMED   12426330
REFERENCE   5  (residues 1 to 719)
  AUTHORS   Doublet,P., Grangeasse,C., Obadia,B., Vaganay,E. and Cozzone,A.J.
  TITLE     Structural organization of the protein-tyrosine autokinase Wzc
            within Escherichia coli cells
  JOURNAL   J. Biol. Chem. 277 (40), 37339-37348 (2002)
   PUBMED   12138098
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008568.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11519
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..719
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..719
                     /gene="wzc"
     Protein         1..719
                     /product="tyrosine-protein kinase Wzc"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0009103 - lipopolysaccharide biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=78983
     Region          1..718
                     /region_name="PRK11519"
                     /note="tyrosine-protein kinase Wzc"
                     /db_xref="CDD:183173"
     Site            order(507,510..511,513..515,535,563,565..566,608,617,620,
                     643..644,646..649,652..653,656,668..669,671,673..674,677,
                     681,684..685)
                     /site_type="other"
                     /note="oligomer interface [polypeptide binding]"
                     /db_xref="CDD:349772"
     Site            order(536..541,563,568,641,695)
                     /site_type="active"
                     /db_xref="CDD:349772"
ORIGIN      
        1 mtekakqsaa vtgsdeidig rlvgtviear wwvlgttaif alcaviytff atpiysadal
       61 vqieqnagns lvqdinsala nkppasdaei qlirsrlvlg ktvddldldi avtkntfplf
      121 gagwerlmgr hnemvkvttf trpetmsgqi ftlkvlgdkr yqlvsdggfs aqgvvgqpln
      181 kdgvtmrvea idarpdteft vskfstlgmi nnlqnnltvt etgkdtgvls ltftgedrdq
      241 ireilnsitr nylqqdiark seeagkslaf lakqlpevrs rldvaenkln afrqdkdsvd
      301 lpleakavld smvnidaqln eltfkeaeis klftkahpay rtllekrkal edekaklngr
      361 vtampktqqe ivrltrdves gqqvymqlln kqqelkitea stvgdvrivd paitqpgvlk
      421 pkkaliilgs iilglmlsiv gvllrslfnr giespqalee hgisvyasip lsewqkards
      481 vktikgikry kqsqllavgn ptdlaieair slrtslhfam mqaqnnvlml tgvspsigkt
      541 fvcanlaavi sqthkrvlli dcdmrkgyth ellgtnnvdg lsdilagkge iascakptai
      601 anfdliprgq vppnpsellm serfgeliaw assrydlvli dtppilavtd aaivgrhagt
      661 tlmvaryavn tlkevetsls rfdqngiqvk gvilnsifrr atgyqdygyy eyeyqsdsk