MULTISPECIES: translation initiation factor IF-2

LOCUS       WP_000133055             882 aa            linear   BCT 03-JUN-2024
            [Enterobacteriaceae].
ACCESSION   WP_000133055
VERSION     WP_000133055.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 882)
  AUTHORS   Roy,B., Liu,Q., Shoji,S. and Fredrick,K.
  TITLE     IF2 and unique features of initiator tRNAfMet help establish the
            translational reading frame
  JOURNAL   RNA Biol 15 (4-5), 604-613 (2018)
   PUBMED   28914580
REFERENCE   2  (residues 1 to 882)
  AUTHORS   Sacerdot,C., Vachon,G., Laalami,S., Morel-Deville,F., Cenatiempo,Y.
            and Grunberg-Manago,M.
  TITLE     Both forms of translational initiation factor IF2 (alpha and beta)
            are required for maximal growth of Escherichia coli. Evidence for
            two translational initiation codons for IF2 beta
  JOURNAL   J Mol Biol 225 (1), 67-80 (1992)
   PUBMED   1374802
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00487.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..882
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..882
                     /gene="infB"
     Protein         1..882
                     /product="translation initiation factor IF-2"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003743 - translation initiation factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /calculated_mol_wt=96277
     Region          56..94
                     /region_name="IF2_assoc"
                     /note="Bacterial translation initiation factor IF-2
                     associated region; pfam08364"
                     /db_xref="CDD:429947"
     Region          <84..380
                     /region_name="PTZ00121"
                     /note="MAEBL; Provisional"
                     /db_xref="CDD:173412"
     Region          306..356
                     /region_name="IF2_N"
                     /note="Translation initiation factor IF-2, N-terminal
                     region; pfam04760"
                     /db_xref="CDD:428110"
     Region          380..881
                     /region_name="InfB"
                     /note="Translation initiation factor IF-2, a GTPase
                     [Translation, ribosomal structure and biogenesis];
                     COG0532"
                     /db_xref="CDD:440298"
ORIGIN      
        1 mtdvtiktla aerqtsverl vqqfadagir ksaddsvsaq ekqtlidhln qknsgpdklt
       61 lqrktrstln ipgtggksks vqievrkkrt fvkrdpqeae rlaaeeqarr eaeesakrea
      121 qqkaereaae qakreaaeqa kreaaekdkv snqqddmtkn aqaekarreq eaaelkrkae
      181 eearrkleee arrvaeearr maeenkwtdn aeptedssdy hvttsqharq aedesdreve
      241 ggrgrgrnak aarpkkgnkh aeskadreea raavrggkgg krkgsslqqg fqkpaqavnr
      301 dvvigetitv gelankmavk gsqvikammk lgamatinqv idqetaqlva eemghkvilr
      361 reneleeavm sdrdtgaaae prapvvtimg hvdhgktsll dyirstkvas geaggitqhi
      421 gayhveteng mitfldtpgh aaftsmrarg aqatdivvlv vaaddgvmpq tieaiqhaka
      481 aqvpvvvavn kidkpeadpd rvknelsqyg ilpeewgges qfvhvsakag tgidelldai
      541 llqaevlelk avrkgmasga viesfldkgr gpvatvlvre gtlhkgdivl cgfeygrvra
      601 mrnelgqevl eagpsipvei lglsgvpaag devtvvrdek karevalyrq gkfrevklar
      661 qqksklenmf anmtegevhe vnivlkadvq gsveaisdsl lklstdevkv kiigsgvggi
      721 tetdatlaaa snailvgfnv radasarkvi eaesldlryy sviynlidev kaamsgmlsp
      781 elkqqiigla evrdvfkspk fgaiagcmvt egvvkrhnpi rvlrdnvviy egeleslrrf
      841 kddvnevrng mecgigvkny ndvrtgdvie vfeiieiqrt ia