MULTISPECIES: translation initiation factor IF-2

LOCUS       WP_000133044             890 aa            linear   BCT 03-JUN-2024
            [Enterobacteriaceae].
ACCESSION   WP_000133044
VERSION     WP_000133044.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 890)
  AUTHORS   Roy,B., Liu,Q., Shoji,S. and Fredrick,K.
  TITLE     IF2 and unique features of initiator tRNAfMet help establish the
            translational reading frame
  JOURNAL   RNA Biol 15 (4-5), 604-613 (2018)
   PUBMED   28914580
REFERENCE   2  (residues 1 to 890)
  AUTHORS   Sacerdot,C., Vachon,G., Laalami,S., Morel-Deville,F., Cenatiempo,Y.
            and Grunberg-Manago,M.
  TITLE     Both forms of translational initiation factor IF2 (alpha and beta)
            are required for maximal growth of Escherichia coli. Evidence for
            two translational initiation codons for IF2 beta
  JOURNAL   J Mol Biol 225 (1), 67-80 (1992)
   PUBMED   1374802
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00487.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..890
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..890
                     /gene="infB"
     Protein         1..890
                     /product="translation initiation factor IF-2"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003743 - translation initiation factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /calculated_mol_wt=97219
     Region          <19..>281
                     /region_name="PTZ00121"
                     /note="MAEBL; Provisional"
                     /db_xref="CDD:173412"
     Region          56..94
                     /region_name="IF2_assoc"
                     /note="Bacterial translation initiation factor IF-2
                     associated region; pfam08364"
                     /db_xref="CDD:429947"
     Region          314..364
                     /region_name="IF2_N"
                     /note="Translation initiation factor IF-2, N-terminal
                     region; pfam04760"
                     /db_xref="CDD:428110"
     Region          388..889
                     /region_name="InfB"
                     /note="Translation initiation factor IF-2, a GTPase
                     [Translation, ribosomal structure and biogenesis];
                     COG0532"
                     /db_xref="CDD:440298"
ORIGIN      
        1 mtdvtiktla aerqtsverl vqqfadagir ksaddsvsaq ekqtlidhln qknsgpdklt
       61 lqrktrstln ipgtggksks vqievrkkrt fvkrdpqeae rlaaeeqaqr eaeeqarrea
      121 eesakreaqq kaereaaeqa kreaaeqakr eaaekdkvsn qqddmtknaq aekarreqea
      181 aelkrkaeee arrkleeear rvaeearrma eenkwtdnae ptedssdyhv ttsqharqae
      241 desdrevegg rgrgrnakaa rpkkgnkhae skadreeara avrggkggkr kgsslqqgfq
      301 kpaqavnrdv vigetitvge lankmavkgs qvikammklg amatinqvid qetaqlvaee
      361 mghkvilrre neleeavmsd rdtgaaaepr apvvtimghv dhgktslldy irstkvasge
      421 aggitqhiga yhvetengmi tfldtpghaa ftsmrargaq atdivvlvva addgvmpqti
      481 eaiqhakaaq vpvvvavnki dkpeadpdrv knelsqygil peewggesqf vhvsakagtg
      541 idelldaill qaevlelkav rkgmasgavi esfldkgrgp vatvlvregt lhkgdivlcg
      601 feygrvramr nelgqevlea gpsipveilg lsgvpaagde vtvvrdekka revalyrqgk
      661 frevklarqq ksklenmfan mtegevhevn ivlkadvqgs veaisdsllk lstdevkvki
      721 igsgvggite tdatlaaasn ailvgfnvra dasarkviea esldlryysv iynlidevka
      781 amsgmlspel kqqiiglaev rdvfkspkfg aiagcmvteg vvkrhnpirv lrdnvviyeg
      841 eleslrrfkd dvnevrngme cgigvknynd vrtgdvievf eiieiqrtia