D-alanine--D-alanine ligase [Escherichia coli].

LOCUS       WP_000130066             306 aa            linear   BCT 10-FEB-2020
ACCESSION   WP_000130066
VERSION     WP_000130066.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 306)
  AUTHORS   Fan,C., Park,I.S., Walsh,C.T. and Knox,J.R.
  TITLE     D-alanine:D-alanine ligase: phosphonate and phosphinate
            intermediates with wild type and the Y216F mutant
  JOURNAL   Biochemistry 36 (9), 2531-2538 (1997)
   PUBMED   9054558
REFERENCE   2  (residues 1 to 306)
  AUTHORS   Fan,C., Moews,P.C., Walsh,C.T. and Knox,J.R.
  TITLE     Vancomycin resistance: structure of D-alanine:D-alanine ligase at
            2.3 A resolution
  JOURNAL   Science 266 (5184), 439-443 (1994)
   PUBMED   7939684
REFERENCE   3  (residues 1 to 306)
  AUTHORS   al-Bar,O.A., O'Connor,C.D., Giles,I.G. and Akhtar,M.
  TITLE     D-alanine: D-alanine ligase of Escherichia coli. Expression,
            purification and inhibitory studies on the cloned enzyme
  JOURNAL   Biochem. J. 282 (Pt 3), 747-752 (1992)
   PUBMED   1554356
REFERENCE   4  (residues 1 to 306)
  AUTHORS   Dewar,S.J. and Donachie,W.D.
  TITLE     Regulation of expression of the ftsA cell division gene by
            sequences in upstream genes
  JOURNAL   J. Bacteriol. 172 (11), 6611-6614 (1990)
   PUBMED   2228979
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR006797
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..306
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..306
                     /gene="ddlB"
     Protein         1..306
                     /product="D-alanine--D-alanine ligase"
                     /EC_number="6.3.2.4"
                     /calculated_mol_wt=32723
     Region          1..306
                     /region_name="ddl"
                     /note="D-alanine--D-alanine ligase; Reviewed; PRK01372"
                     /db_xref="CDD:234948"
ORIGIN      
        1 mtdkiavllg gtsaerevsl nsgaavlagl reggidaypv dpkevdvtql ksmgfqkvfi
       61 alhgrggedg tlqgmlelmg lpytgsgvma salsmdklrs kllwqgaglp vapwvaltrv
      121 efekglsdkq laeisalglp vivkpsregs svgmskvvae nalqdalrla fqhdeevlie
      181 kwlsgpeftv ailgeeilps vriqpsgtfy dyeakylsde tqyfcpagle asqeanlqal
      241 vlkawttlgc kgwgridvml dsdgqfylle antspgmtsh slvpmaarqa gmsfsqlvvr
      301 ilelad