terminase large subunit [Escherichia coli].

LOCUS       WP_000127900             553 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_000127900
VERSION     WP_000127900.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 553)
  AUTHORS   Fung,H.K.H., Grimes,S., Huet,A., Duda,R.L., Chechik,M., Gault,J.,
            Robinson,C.V., Hendrix,R.W., Jardine,P.J., Conway,J.F.,
            Baumann,C.G. and Antson,A.A.
  TITLE     Structural basis of DNA packaging by a ring-type ATPase from an
            archetypal viral system
  JOURNAL   Nucleic Acids Res 50 (15), 8719-8732 (2022)
   PUBMED   35947691
REFERENCE   2  (residues 1 to 553)
  AUTHORS   Xu,R.G., Jenkins,H.T., Chechik,M., Blagova,E.V., Lopatina,A.,
            Klimuk,E., Minakhin,L., Severinov,K., Greive,S.J. and Antson,A.A.
  TITLE     Viral genome packaging terminase cleaves DNA using the canonical
            RuvC-like two-metal catalysis mechanism
  JOURNAL   Nucleic Acids Res 45 (6), 3580-3590 (2017)
   PUBMED   28100693
REFERENCE   3  (residues 1 to 553)
  AUTHORS   Black,L.W.
  TITLE     DNA packaging in dsDNA bacteriophages
  JOURNAL   Annu Rev Microbiol 43, 267-292 (1989)
   PUBMED   2679356
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11468530
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..553
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..553
                     /product="terminase large subunit"
                     /EC_number="3.6.4.-"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0140657 - ATP-dependent activity
                     [Evidence IEA]"
                     /calculated_mol_wt=62394
     Region          1..535
                     /region_name="YmfN"
                     /note="Phage terminase-like protein, large subunit,
                     contains N-terminal HTH domain [Mobilome: prophages,
                     transposons]; COG4626"
                     /db_xref="CDD:443665"
ORIGIN      
        1 mtawnkyaed vktgkipack rlkqavkryf sdlksplytf drevverfia fsrvcphvkg
       61 pmrgrpiele pwqqfafaci lgfkvkatgr rkytsafiev prknakstta ailanwflim
      121 engqqdiyta avsrdqariv fddarqmcll srplrrrvni qahkvihpks nsllkplaak
      181 aatiegttps laivdeyhlh pdngvysale lgmgarpegl lfaittsgsn vvsackqhyd
      241 yccqildgee vnesmfvliy elddesevdd pamwikanpn idvsvdrekl astiqkargi
      301 psqwvemmtk rfniwcqgat pwmgngawae cagtfteedl hgqecyagld lsstsdissv
      361 cyafpvgkti mlisrhylpe fqlqnpankn ravyrqwaka gwirttpgdc idydrirddi
      421 mqdaekfhir lvgfdtwnat hlrtqlqgag fevepfpqty lrfspaaksf evfvnrrviv
      481 hrgdpvlsws msnvvmqsda nanikpnkkk spnkidpsva almafgtfqa ehedfafdis
      541 dshrqkleef sgv