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MULTISPECIES: (d)CMP kinase [Enterobacteriaceae].


LOCUS       WP_000125016             227 aa            linear   BCT 04-JUN-2024
ACCESSION   WP_000125016
VERSION     WP_000125016.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 227)
  AUTHORS   Thum,C., Schneider,C.Z., Palma,M.S., Santos,D.S. and Basso,L.A.
  TITLE     The Rv1712 Locus from Mycobacterium tuberculosis H37Rv codes for a
            functional CMP kinase that preferentially phosphorylates dCMP
  JOURNAL   J Bacteriol 191 (8), 2884-2887 (2009)
   PUBMED   19181797
REFERENCE   2  (residues 1 to 227)
  AUTHORS   Briozzo,P., Golinelli-Pimpaneau,B., Gilles,A.M., Gaucher,J.F.,
            Burlacu-Miron,S., Sakamoto,H., Janin,J. and Barzu,O.
  TITLE     Structures of escherichia coli CMP kinase alone and in complex with
            CDP: a new fold of the nucleoside monophosphate binding domain and
            insights into cytosine nucleotide specificity
  JOURNAL   Structure 6 (12), 1517-1527 (1998)
   PUBMED   9862805
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00017.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..227
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..227
                     /gene="cmk"
     Protein         1..227
                     /product="(d)CMP kinase"
                     /EC_number="2.7.4.25"
                     /GO_function="GO:0004127 - cytidylate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0015949 - nucleobase-containing small
                     molecule interconversion [Evidence IEA]"
                     /calculated_mol_wt=24615
     Region          6..225
                     /region_name="Cmk"
                     /note="Cytidylate kinase [Nucleotide transport and
                     metabolism]; COG0283"
                     /db_xref="CDD:440052"
ORIGIN      
        1 mtaiapviti dgpsgagkgt lckamaealq whlldsgaiy rvlalaalhh hvdvasedal
       61 vplashldvr fvstngnlev ilegedvsge irtqevanaa sqvaafprvr eallrrqraf
      121 relpgliadg rdmgtvvfpd apvkifldas seerahrrml qlqekgfsvn ferllaeike
      181 rddrdrnrav aplvpaadal vldsttlsie qviekalqya rqklala