S49 family peptidase [Escherichia coli].

LOCUS       WP_000123254             439 aa            linear   BCT 23-JUL-2024
ACCESSION   WP_000123254
VERSION     WP_000123254.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 439)
  AUTHORS   Rawlings,N.D. and Barrett,A.J.
  TITLE     Families of serine peptidases
  JOURNAL   Methods Enzymol 244, 19-61 (1994)
   PUBMED   7845208
REFERENCE   2  (residues 1 to 439)
  AUTHORS   Rawlings,N.D. and Barrett,A.J.
  TITLE     Evolutionary families of peptidases
  JOURNAL   Biochem J 290 (Pt 1) (Pt 1), 205-218 (1993)
   PUBMED   8439290
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10161638
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..439
                     /product="S49 family peptidase"
                     /EC_number="3.4.21.-"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /calculated_mol_wt=45646
     Region          81..293
                     /region_name="S49_Sppa_36K_type"
                     /note="Signal peptide peptidase A (SppA) 36K type, a
                     serine protease, has catalytic Ser-Lys dyad; cd07022"
                     /db_xref="CDD:132933"
     Site            order(88,129,166,181,183,191..194,243,266..268,270,273)
                     /site_type="other"
                     /note="tandem repeat interface [polypeptide binding]"
                     /db_xref="CDD:132933"
     Site            order(108,115,141,207,209..213,241,245)
                     /site_type="other"
                     /note="oligomer interface [polypeptide binding]"
                     /db_xref="CDD:132933"
     Site            166
                     /site_type="active"
                     /note="active site residues [active]"
                     /db_xref="CDD:132933"
ORIGIN      
        1 mtaelrnlph iasmafnepl mlepayarvf fcalagqlgi srltdavsgd sltageapaa
       61 lalsgdddgp rqarsyqvmn giavlpvsgt lvsrtralqp ysgmtgyngi iarlqqaasd
      121 pmvdgilldm dtpggmvaga fdcadiiarv rdikpvwala ndmncsagql lasaasrrlv
      181 tqtartgsig vmmahsnyga alekqgveit liysgshkvd gnpyshlpgd vretlqsrmd
      241 atrrmfaqkv saytglsvqa vldteaavys gqeaidagla delvnstdai tvmrdaldar
      301 ksrlsggrmt ketqsttvsa tasqadvtgv vpategenas aaqpdvnaqi taavaaensr
      361 imgilnceea hgreeqarvl aetpgmtvet arrilaaapq saqarsdtal drlmqgapap
      421 laagnpasda vndllntpv