8-amino-7-oxononanoate synthase [Escherichia coli].

LOCUS       WP_000118816             384 aa            linear   BCT 20-JUN-2019
ACCESSION   WP_000118816
VERSION     WP_000118816.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00858.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..384
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..384
                     /gene="bioF"
     Protein         1..384
                     /product="8-amino-7-oxononanoate synthase"
                     /EC_number="2.3.1.47"
                     /GO_function="GO:0008710 - 8-amino-7-oxononanoate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=41489
     Region          1..382
                     /region_name="PRK05958"
                     /note="8-amino-7-oxononanoate synthase; Reviewed"
                     /db_xref="CDD:235655"
     Site            order(47,107..109,133,175,179..180,204,206..207,233,236,
                     361)
                     /site_type="active"
                     /note="substrate-cofactor binding pocket [active]"
                     /db_xref="CDD:99747"
     Site            order(107..109,133,175,179,204,206..207,233,236)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]"
                     /db_xref="CDD:99747"
     Site            236
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99747"
ORIGIN      
        1 mswqekinaa ldarraadal rrrypvaqga grwlvaddrq ylnfssndyl glshhpqiir
       61 awkqgaeqfg vgsggsghvs gysvahqale eelaewlgys rallfisgfa anqaviaamm
      121 akedrivadr lshaslleaa slspsqlrrf vhndvthlar llaspcpgqq lvvtegvfsm
      181 dgdsaplaei qqvtqqhngw lmvddahgtg vigeqgrgtc wlqkvkpell vvtfgkgfgv
      241 sgaavlcsst vadyllqfar hliystsmpp aqaqalrasl avirsdegda rreklaalit
      301 rfragvqdlp ftladscsai qplivgdnsr alqlaeklrq qgcwvtairp ptvpsgtarl
      361 rltltaahem qdidrllevl hgng