MULTISPECIES:

LOCUS       WP_000116392             556 aa            linear   BCT 04-JUN-2024
            2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid
            synthase [Salmonella].
ACCESSION   WP_000116392
VERSION     WP_000116392.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 556)
  AUTHORS   Jiang,M., Cao,Y., Guo,Z.F., Chen,M., Chen,X. and Guo,Z.
  TITLE     Menaquinone biosynthesis in Escherichia coli: identification of
            2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate as a
            novel intermediate and re-evaluation of MenD activity
  JOURNAL   Biochemistry 46 (38), 10979-10989 (2007)
   PUBMED   17760421
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00173.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..556
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..556
                     /gene="menD"
     Protein         1..556
                     /product="2-succinyl-5-enolpyruvyl-6-hydroxy-3-
                     cyclohexene-1-carboxylic-acid synthase"
                     /EC_number="2.2.1.9"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0070204 -
                     2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-
                     carboxylic-acid synthase activity [Evidence IEA]"
                     /GO_process="GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=61392
     Region          2..556
                     /region_name="MenD"
                     /note="2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-
                     carboxylate synthase [Coenzyme transport and metabolism];
                     COG1165"
                     /db_xref="CDD:440779"
ORIGIN      
        1 msvsafnrrw aavilealtr hgvrhvciap gsrstpltla aaenpafihh thfderglgh
       61 lalglakvsq qpvavivtsg tavanlypal ieagltgekl illtadrppe lidcganqai
      121 rqagmfashp sqtlslprpt qdiparwlvs tidnalamlh agalhincpf aeplygdmnd
      181 tglvwqqrlg dwwqdekpwl rearrlesdk qrdwffwrqk rgvvvagrms aeegkkvaqw
      241 aqtlgwplig dvlsqtgqpl pcadlwlgna kavtelqqaq ivvqlgsslt gkrllqwqat
      301 cepeeywvid niegrldpah hrgrrlvaki adwlelhpae krkpwcveip rlaelawqrv
      361 vaqrdtfgea qlahrirdyl peqgqlfvgn slvvrlidal sqlpagypvy snrgasgidg
      421 llstaagvqr asakstlaiv gdlsalydln alallrqvsa pfvlivvnnn ggqifsllpt
      481 pqskrerfyl mpqnvhfdha aamfnlryhr penweelesa lagawrtpat tvielvvndt
      541 dgaqtlqqll aqvshl