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glycosyltransferase family 2 protein [Escherichia coli].


LOCUS       WP_000115645             558 aa            linear   BCT 23-DEC-2024
ACCESSION   WP_000115645
VERSION     WP_000115645.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 558)
  AUTHORS   Coutinho,P.M., Deleury,E., Davies,G.J. and Henrissat,B.
  TITLE     An evolving hierarchical family classification for
            glycosyltransferases
  JOURNAL   J Mol Biol 328 (2), 307-317 (2003)
   PUBMED   12691742
REFERENCE   2  (residues 1 to 558)
  AUTHORS   Oriol,R., Martinez-Duncker,I., Chantret,I., Mollicone,R. and
            Codogno,P.
  TITLE     Common origin and evolution of glycosyltransferases using
            Dol-P-monosaccharides as donor substrate
  JOURNAL   Mol Biol Evol 19 (9), 1451-1463 (2002)
   PUBMED   12200473
REFERENCE   3  (residues 1 to 558)
  AUTHORS   Kapitonov,D. and Yu,R.K.
  TITLE     Conserved domains of glycosyltransferases
  JOURNAL   Glycobiology 9 (10), 961-978 (1999)
   PUBMED   10521532
REFERENCE   4  (residues 1 to 558)
  AUTHORS   Breton,C. and Imberty,A.
  TITLE     Structure/function studies of glycosyltransferases
  JOURNAL   Curr Opin Struct Biol 9 (5), 563-571 (1999)
   PUBMED   10508766
REFERENCE   5  (residues 1 to 558)
  AUTHORS   Campbell,J.A., Davies,G.J., Bulone,V. V and Henrissat,B.
  TITLE     A classification of nucleotide-diphospho-sugar glycosyltransferases
            based on amino acid sequence similarities
  JOURNAL   Biochem J 329 (Pt 3) (Pt 3), 719 (1998)
   PUBMED   9445404
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10135282
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..558
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..558
                     /product="glycosyltransferase family 2 protein"
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /calculated_mol_wt=62560
     Region          9..190
                     /region_name="DPM_DPG-synthase_like"
                     /note="DPM_DPG-synthase_like is a member of the
                     Glycosyltransferase 2 superfamily; cd04179"
                     /db_xref="CDD:133022"
     Site            order(12,14,95)
                     /site_type="active"
                     /note="Ligand binding site [active]"
                     /db_xref="CDD:133022"
     Site            order(39,94..95)
                     /site_type="active"
                     /note="Putative Catalytic site [active]"
                     /db_xref="CDD:133022"
     Site            93..95
                     /site_type="active"
                     /note="DXD motif [active]"
                     /db_xref="CDD:133022"
     Region          249..553
                     /region_name="COG4261"
                     /note="Predicted acyltransferase, LPLAT superfamily
                     [General function prediction only]"
                     /db_xref="CDD:443403"
ORIGIN      
        1 msvnfspcvl ipcynhgamm pgvlarlkpf nlpcivvddg sdattqqqld sllaeqpgvt
       61 lirlaenagk gaavmrglqa aadagfshav qvdadgqhai edipkllala eqqpaalisg
      121 qpiyddsipr srlygrwvth vwvwietlsl qlkdsmcgfr vypvaptlql akhatigkrm
      181 dfdtevmvrl ywqgntsyfv ptrvtypldg lshfdalkdn vrislmhtrl ffgmlprips
      241 llmrrsschw arqsevkglw gmrlmllvwr llgrtafsal lypvvgvywl tasrarkasq
      301 dwlarvrqhq pqaaklnsyq hflrfgnaml dkiaswrgel qpgrdvlfap gaeaaldvrd
      361 prgklllash lgdvevcral akiqgyktin alvfsenaqr fkqimqemap qaginlmpvt
      421 digpetaill kekldngewv aivgdriavn pqrggdwrvc wssfmgqpap fpqgpfilas
      481 ilrcpvnlif alrqhgklhi hcesfadplq lprgerqqal qnaidhyaar lehyalqspl
      541 dwfnffdfwq lpeiqdke