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3'3'-cGAMP-specific phosphodiesterase [Vibrio cholerae].


LOCUS       WP_000109470             460 aa            linear   BCT 09-APR-2020
ACCESSION   WP_000109470
VERSION     WP_000109470.1
KEYWORDS    RefSeq.
SOURCE      Vibrio cholerae
  ORGANISM  Vibrio cholerae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Vibrio.
REFERENCE   1  (residues 1 to 460)
  AUTHORS   Deng,M.J., Tao,J., E,C., Ye,Z.Y., Jiang,Z., Yu,J. and Su,X.D.
  TITLE     Novel Mechanism for Cyclic Dinucleotide Degradation Revealed by
            Structural Studies of Vibrio Phosphodiesterase V-cGAP3
  JOURNAL   J. Mol. Biol. 430 (24), 5080-5093 (2018)
   PUBMED   30365951
REFERENCE   2  (residues 1 to 460)
  AUTHORS   Gao,J., Tao,J., Liang,W., Zhao,M., Du,X., Cui,S., Duan,H., Kan,B.,
            Su,X. and Jiang,Z.
  TITLE     Identification and characterization of phosphodiesterases that
            specifically degrade 3'3'-cyclic GMP-AMP
  JOURNAL   Cell Res. 25 (5), 539-550 (2015)
   PUBMED   25837739
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011794
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Vibrio cholerae"
                     /db_xref="taxon:666"
     Protein         1..460
                     /product="3'3'-cGAMP-specific phosphodiesterase"
                     /calculated_mol_wt=51194
     Region          <10..230
                     /region_name="HDGYP"
                     /note="HD-GYP domain, c-di-GMP phosphodiesterase class II
                     (or its inactivated variant) [Signal transduction
                     mechanisms]; COG2206"
                     /db_xref="CDD:441808"
     Region          138..447
                     /region_name="HDGYP"
                     /note="HD-GYP domain, c-di-GMP phosphodiesterase class II
                     (or its inactivated variant) [Signal transduction
                     mechanisms]; COG2206"
                     /db_xref="CDD:441808"
ORIGIN      
        1 msvaqntfpl selmisltta ldmtegqppe hcirccwigm higmqlelse pelhdlfftl
       61 llkdagcssn aaricelyat ddltfkrryk tvgtslssvi nfivkntgse qswteriltt
      121 idilkngndy aqeliqtrct rgadvarelr fseavaqgih sldehwngqg rpeqrkgeai
      181 plfsrialla qvfdvfqmeh sieealqeim arsgvwfdpk lvevveqlfe nprflsglka
      241 tdisqrvmnl ppaqahlpld daylecivta fgkivdaksp ytaghserva vytdliarql
      301 aisdadriwl rraallhdig klgvsnaild kpgkldeaew ravqahaayt eqilyklspf
      361 ktlarmagah hekldgtgyp rgvngdeisl mtriittadi fdalsaerpy raampidkal
      421 aimeenlhta idpecfaalk kalnllpdey tqlphssdnt