MULTISPECIES: SIS domain-containing protein [Salmonella].

LOCUS       WP_000109360             328 aa            linear   BCT 20-MAR-2023
ACCESSION   WP_000109360
VERSION     WP_000109360.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 328)
  AUTHORS   Bateman,A.
  TITLE     The SIS domain: a phosphosugar-binding domain
  JOURNAL   Trends Biochem Sci 24 (3), 94-95 (1999)
   PUBMED   10203754
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11454870
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..328
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     Protein         1..328
                     /product="SIS domain-containing protein"
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0097367 - carbohydrate derivative binding
                     [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=36597
     Region          4..326
                     /region_name="AgaS"
                     /note="Fructoselysine-6-P-deglycase FrlB or related
                     protein, duplicated sugar isomerase (SIS) domain [Cell
                     wall/membrane/envelope biogenesis]; COG2222"
                     /db_xref="CDD:441824"
     Region          23..148
                     /region_name="SIS_1"
                     /note="A subgroup of the SIS domain. SIS (Sugar ISomerase)
                     domains are found in many phosphosugar isomerases and
                     phosphosugar binding proteins. SIS domains are also found
                     in proteins that regulate the expression of genes involved
                     in synthesis of phosphosugars; cd05710"
                     /db_xref="CDD:240214"
     Site            order(32,78)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:240214"
ORIGIN      
        1 msvahenarr iisdilgkqn iervwfvgcg gsltgfwpgk yfldceaskl avgyitsnef
       61 vhatpkalgk nsvvilasqq gntaetvaaa rvarekgaat iglvyqpdtp lceysdyiie
      121 yqwarypetv dpaqqkaays lwlaleilaq tegyaqydel vsafgrfsdv vhgaqrqvqe
      181 daqrfaaewk dekvvymmgs gpsfgaahqe sicillemqw insasihsge yfhgpfeite
      241 pgtpfillqs sgrtrplddr airfieryqg klqlidadkl giqdlstdvg eyfcgllhnc
      301 vldvynlala tarnhplttr rymwkvey