Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: monothiol glutaredoxin 4 [Enterobacteriaceae].


LOCUS       WP_000108172             115 aa            linear   BCT 16-DEC-2020
ACCESSION   WP_000108172
VERSION     WP_000108172.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 115)
  AUTHORS   Iwema,T., Picciocchi,A., Traore,D.A., Ferrer,J.L., Chauvat,F. and
            Jacquamet,L.
  TITLE     Structural basis for delivery of the intact [Fe2S2] cluster by
            monothiol glutaredoxin
  JOURNAL   Biochemistry 48 (26), 6041-6043 (2009)
   PUBMED   19505088
REFERENCE   2  (residues 1 to 115)
  AUTHORS   Fladvad,M., Bellanda,M., Fernandes,A.P., Mammi,S.,
            Vlamis-Gardikas,A., Holmgren,A. and Sunnerhagen,M.
  TITLE     Molecular mapping of functionalities in the solution structure of
            reduced Grx4, a monothiol glutaredoxin from Escherichia coli
  JOURNAL   J. Biol. Chem. 280 (26), 24553-24561 (2005)
   PUBMED   15840565
REFERENCE   3  (residues 1 to 115)
  AUTHORS   Fernandes,A.P., Fladvad,M., Berndt,C., Andresen,C., Lillig,C.H.,
            Neubauer,P., Sunnerhagen,M., Holmgren,A. and Vlamis-Gardikas,A.
  TITLE     A novel monothiol glutaredoxin (Grx4) from Escherichia coli can
            serve as a substrate for thioredoxin reductase
  JOURNAL   J. Biol. Chem. 280 (26), 24544-24552 (2005)
   PUBMED   15833738
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            REFSEQ INFORMATION: The reference sequence is identical to P0AC69.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR010981
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..115
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..115
                     /gene="grxD"
     Protein         1..115
                     /product="monothiol glutaredoxin 4"
                     /calculated_mol_wt=12748
     Region          1..115
                     /region_name="PRK10824"
                     /note="Grx4 family monothiol glutaredoxin"
                     /db_xref="CDD:182759"
     Site            order(22,30..32,70..71)
                     /site_type="other"
                     /note="putative GSH binding site [chemical binding]"
                     /db_xref="CDD:239326"
     Site            order(30,33)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:239326"
ORIGIN      
        1 msttiekiqr qiaenpilly mkgspklpsc gfsaqavqal aacgerfayv dilqnpdira
       61 elpkyanwpt fpqlwvdgel vggcdiviem yqrgelqqli ketaakykse epdae