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Zn(II)/Cd(II)/Pb(II) translocating P-type ATPase ZntA [Escherichia


LOCUS       WP_000106562             732 aa            linear   BCT 17-OCT-2022
            coli].
ACCESSION   WP_000106562
VERSION     WP_000106562.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 732)
  AUTHORS   Mitra,B. and Sharma,R.
  TITLE     The cysteine-rich amino-terminal domain of ZntA, a
            Pb(II)/Zn(II)/Cd(II)-translocating ATPase from Escherichia coli, is
            not essential for its function
  JOURNAL   Biochemistry 40 (25), 7694-7699 (2001)
   PUBMED   11412123
REFERENCE   2  (residues 1 to 732)
  AUTHORS   Rensing,C., Mitra,B. and Rosen,B.P.
  TITLE     The zntA gene of Escherichia coli encodes a Zn(II)-translocating
            P-type ATPase
  JOURNAL   Proc Natl Acad Sci U S A 94 (26), 14326-14331 (1997)
   PUBMED   9405611
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF033775.1
            Evidence Source    :: NCBIFAM
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..732
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..732
                     /gene="zntA"
     Protein         1..732
                     /product="Zn(II)/Cd(II)/Pb(II) translocating P-type ATPase
                     ZntA"
                     /EC_number="7.2.2.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0019829 - ATPase-coupled cation
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006812 - cation transport [Evidence IEA]"
                     /calculated_mol_wt=76593
     Region          1..732
                     /region_name="P_type_ZntA"
                     /note="Zn(II)/Cd(II)/Pb(II) translocating P-type ATPase
                     ZntA; NF033775"
                     /db_xref="CDD:468183"
ORIGIN      
        1 mstpdnhgkk apqfaafkpl ttvqnandcc cdgacsstpt lsenvsgtry swkvsgmdca
       61 acarkvenav rqlagvnqvq vlfateklvv dadndiraqv esavqkagys lrdeqaadep
      121 qasrlkenlp litlivmmai swgleqfnhp fgqlafiatt lvglypiarq alrliksgsy
      181 faietlmsva aigalfigat aeaamvlllf ligerlegwa asrarqgvsa lmalkpetat
      241 rlrngereev ainslrpgdv ievaaggrlp adgkllspfa sfdesaltge sipveratgd
      301 kvpagatsvd rlvtlevlse pgasaidril klieeaeerr apierfidrf sriytpaima
      361 vallvtlvpp llfatswqew iykgltllli gcpcalvist paaitsglaa aarrgalikg
      421 gaaleqlgrv tqvafdktgt ltvgkprvta ihpatgises elltlaaave qgathplaqa
      481 ivreaqvaal aipaaesqra lvgsgieaqv ngervlicaa gkhpadafag linelesagq
      541 tvvlvvrndd vlgiialqdt lradaatais elnalgvkgv iltgdnpraa aaiagelgle
      601 fkagllpedk vkavtelnqh aplamvgdgi ndapamkaaa igiamgsgtd valetadaal
      661 thnhlrglvq mielaratha nirqnitial glkgiflvtt llgmtglwla vladtgatvl
      721 vtanalrllr rr