terminase TerL endonuclease subunit [Escherichia coli].

LOCUS       WP_000104929             455 aa            linear   BCT 28-FEB-2025
ACCESSION   WP_000104929
VERSION     WP_000104929.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 455)
  AUTHORS   Xu,R.G., Jenkins,H.T., Chechik,M., Blagova,E.V., Lopatina,A.,
            Klimuk,E., Minakhin,L., Severinov,K., Greive,S.J. and Antson,A.A.
  TITLE     Viral genome packaging terminase cleaves DNA using the canonical
            RuvC-like two-metal catalysis mechanism
  JOURNAL   Nucleic Acids Res 45 (6), 3580-3590 (2017)
   PUBMED   28100693
REFERENCE   2  (residues 1 to 455)
  AUTHORS   Hilbert,B.J., Hayes,J.A., Stone,N.P., Duffy,C.M., Sankaran,B. and
            Kelch,B.A.
  TITLE     Structure and mechanism of the ATPase that powers viral genome
            packaging
  JOURNAL   Proc Natl Acad Sci U S A 112 (29), E3792-E3799 (2015)
   PUBMED   26150523
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF042863.4
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF20441.4
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..455
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     Protein         1..455
                     /product="terminase TerL endonuclease subunit"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /calculated_mol_wt=50740
     Region          17..70
                     /region_name="HTH_36"
                     /note="Helix-turn-helix domain; pfam13730"
                     /db_xref="CDD:463970"
     Region          <62..453
                     /region_name="YmfN"
                     /note="Phage terminase-like protein, large subunit,
                     contains N-terminal HTH domain [Mobilome: prophages,
                     transposons]; COG4626"
                     /db_xref="CDD:443665"
ORIGIN      
        1 mstkltgyvw dgcaasgmkl ssvaimarla dfsndegvcw psietiarqi gagmstvrta
       61 iarleaegwl trkarrqgdg ssphcavvde yhehatdaly ttmltgmgar rqplmwaitt
      121 agyniegpcy dkrrevieml ngsvpndelf giiytvdegd dwtdpqvlek anpnigvsvy
      181 refllsqqqr aknnarlanv fktkhlniwa sarsayfnlv swqscedksl tleqfegqpc
      241 ilafdlarkl dmnsmarlyt reidgkthyy svaprfwvpy dtvysvekne drrtaerfqk
      301 wvemgvltvt dgaevdyryi leeakaanki spvsespidp fgatglshdl adedlnpvti
      361 iqnytnmsdp mkeleaaies grfhhdgnpi mtwcignvvg ktipgnddvv kpvkeqaenk
      421 idgavalima vgramlyeke dtlsdhiesy girsl