Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: cadaverine/lysine antiporter [Salmonella].


LOCUS       WP_000100008             443 aa            linear   BCT 10-DEC-2019
ACCESSION   WP_000100008
VERSION     WP_000100008.1
KEYWORDS    RefSeq.
SOURCE      Salmonella
  ORGANISM  Salmonella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 443)
  AUTHORS   Moreau,P.L.
  TITLE     The lysine decarboxylase CadA protects Escherichia coli starved of
            phosphate against fermentation acids
  JOURNAL   J. Bacteriol. 189 (6), 2249-2261 (2007)
   PUBMED   17209032
REFERENCE   2  (residues 1 to 443)
  AUTHORS   Soksawatmaekhin,W., Uemura,T., Fukiwake,N., Kashiwagi,K. and
            Igarashi,K.
  TITLE     Identification of the cadaverine recognition site on the
            cadaverine-lysine antiporter CadB
  JOURNAL   J. Biol. Chem. 281 (39), 29213-29220 (2006)
   PUBMED   16877381
REFERENCE   3  (residues 1 to 443)
  AUTHORS   Greenacre,E.J., Lucchini,S., Hinton,J.C. and Brocklehurst,T.F.
  TITLE     The lactic acid-induced acid tolerance response in Salmonella
            enterica serovar Typhimurium induces sensitivity to hydrogen
            peroxide
  JOURNAL   Appl. Environ. Microbiol. 72 (8), 5623-5625 (2006)
   PUBMED   16885318
REFERENCE   4  (residues 1 to 443)
  AUTHORS   Soksawatmaekhin,W., Kuraishi,A., Sakata,K., Kashiwagi,K. and
            Igarashi,K.
  TITLE     Excretion and uptake of cadaverine by CadB and its physiological
            functions in Escherichia coli
  JOURNAL   Mol. Microbiol. 51 (5), 1401-1412 (2004)
   PUBMED   14982633
REFERENCE   5  (residues 1 to 443)
  AUTHORS   Neely,M.N. and Olson,E.R.
  TITLE     Kinetics of expression of the Escherichia coli cad operon as a
            function of pH and lysine
  JOURNAL   J. Bacteriol. 178 (18), 5522-5528 (1996)
   PUBMED   8808945
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007754.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10435
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..443
                     /organism="Salmonella"
                     /db_xref="taxon:590"
     gene            1..443
                     /gene="cadB"
     Protein         1..443
                     /product="cadaverine/lysine antiporter"
                     /GO_function="GO:0043872 - lysine:cadaverine antiporter
                     activity [Evidence IEA]"
                     /calculated_mol_wt=46547
     Region          1..435
                     /region_name="cadB"
                     /note="cadaverine/lysine antiporter; PRK10435"
                     /db_xref="CDD:182458"
ORIGIN      
        1 mssvkkiglf actgvvagnm mgsgiallpa nlasiggiai wgwvisiiga mslayvyarl
       61 atknpqqggp iayageispa fgfqtgvlyy hanwignlai gitavsylst ffpalnnpip
      121 agiaciaivw lftfinmlgg awvsrlttig lflvlipvvl tavagwhwfd iatyhanwnt
      181 stttdshaiv ksillclwaf vgvesaavst gmvknpkrtv platmlgtal agiiyiaatq
      241 viagmfpasv massgapfai ststilggwa aplvsaftaf acltslgswm mlvgqagvra
      301 andgnfpkiy gemdkngipk kglllaavkm talmilitim nssggkasdl fgeltgiavl
      361 ltmlpyfysc vdlirfegfn irnsvslics vlgcafcfia lmgassfels gtfivsliil
      421 mfygrkmhqr qnndsdnnta eal