adenosylmethionine--8-amino-7-oxononanoate transaminase [Shigella

LOCUS       WP_000099955             466 aa            linear   BCT 19-JUN-2019
            flexneri].
ACCESSION   WP_000099955
VERSION     WP_000099955.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF005940.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK07986
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     gene            1..466
                     /gene="bioA"
     Protein         1..466
                     /product="adenosylmethionine--8-amino-7-oxononanoate
                     transaminase"
                     /EC_number="2.6.1.62"
                     /GO_function="GO:0004015 -
                     adenosylmethionine-8-amino-7-oxononanoate transaminase
                     activity [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=51426
     Region          38..465
                     /region_name="PRK07986"
                     /note="adenosylmethionine--8-amino-7-oxononanoate
                     transaminase; Validated"
                     /db_xref="CDD:181189"
     Site            order(148..150,181..182,184,248,282,284..285,311)
                     /site_type="active"
                     /note="inhibitor-cofactor binding pocket [active]"
                     /db_xref="CDD:99735"
     Site            order(149..150,181..182,248,282,285,311)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]"
                     /db_xref="CDD:99735"
     Site            311
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99735"
ORIGIN      
        1 mssvggepwg fsktcfllli rcrlvnlnlf nlvyksimtt ddlafdqrhi whpytsmtsp
       61 lpvypvasae gcelilsdgr rlvdgmssww aaihgynhpq lnaamktqid amshvmfggi
      121 thapaielcr klvamtpqpl ecvfladsgs vavevamkma lqywqakgea rqrfltfrng
      181 yhgdtfgams vcdpdnsmhs lwkgylpenl fapapqsrmd gewderdmvg farlmaahrh
      241 eiaaviiepi vqgaggmrmy hpewlkrirk mcdregilli adeiatgfgr tgklfaceya
      301 eiapdilclg kaltggtmtl satlttreva etisngeagc fmhgptfmgn placaaanas
      361 laiiesgewq qqvaaievql reqlaparda emvadvrvlg aigvvettrp vnmaalqkff
      421 veqgvwirpf gkliylmppy iilpqqlqrl taavnravqd etffcq