Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

MULTISPECIES: muropeptide MFS transporter AmpG


LOCUS       WP_000098429             491 aa            linear   BCT 16-DEC-2020
            [Enterobacteriaceae].
ACCESSION   WP_000098429
VERSION     WP_000098429.1
KEYWORDS    RefSeq.
SOURCE      Enterobacteriaceae
  ORGANISM  Enterobacteriaceae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales.
REFERENCE   1  (residues 1 to 491)
  AUTHORS   Chahboune,A., Decaffmeyer,M., Brasseur,R. and Joris,B.
  TITLE     Membrane topology of the Escherichia coli AmpG permease required
            for recycling of cell wall anhydromuropeptides and AmpC
            beta-lactamase induction
  JOURNAL   Antimicrob. Agents Chemother. 49 (3), 1145-1149 (2005)
   PUBMED   15728916
REFERENCE   2  (residues 1 to 491)
  AUTHORS   Cheng,Q. and Park,J.T.
  TITLE     Substrate specificity of the AmpG permease required for recycling
            of cell wall anhydro-muropeptides
  JOURNAL   J. Bacteriol. 184 (23), 6434-6436 (2002)
   PUBMED   12426329
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008238.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11010
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Enterobacteriaceae"
                     /db_xref="taxon:543"
     gene            1..491
                     /gene="ampG"
     Protein         1..491
                     /product="muropeptide MFS transporter AmpG"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=53114
     Region          1..490
                     /region_name="ampG"
                     /note="muropeptide MFS transporter AmpG; PRK11010"
                     /db_xref="CDD:182898"
     Site            order(24..25,28..29,32,62,121..122,124..126,129,145,
                     148..149,152,231,234..235,238..240,243,272,276,333..334,
                     338,342,358,361..362,365..366,369)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:341039"
ORIGIN      
        1 mssqylrifq qprsaillil gfasglplal tsgtlqawmt venidlktig ffslvgqayv
       61 fkflwsplmd rytppffgrr rgwllatqil llvaiaamgf lepgtqlrwm aalavviafc
      121 sasqdivfda wktdvlpaee rgagaaisvl gyrlgmlvsg glalwladkw lgwqgmywlm
      181 aallipciia tllapeptdt ipvpktleqa vvaplrdffg rnnawlilll ivlyklgdaf
      241 amsltttfli rgvgfdagev gvvnktlgll ativgalygg ilmqrlslfr allifgilqg
      301 asnagywlls itdkhlysmg aavffenlcg gmgtsafval lmtlcnksfs atqfallsal
      361 savgrvyvgp vagwfveahg wstfylfsva aavpglilll vcrqtleytr vndnfisrta
      421 ypagyafamw tlaagvslla vwlllltmda ldlthfsflp allevgvlva lsgvvlggll
      481 dylalrkthl t