4-aminobutyrate--2-oxoglutarate transaminase [Escherichia coli].

LOCUS       WP_000097647             426 aa            linear   BCT 06-NOV-2024
ACCESSION   WP_000097647
VERSION     WP_000097647.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF005985.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK08088
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..426
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..426
                     /gene="gabT"
     Protein         1..426
                     /product="4-aminobutyrate--2-oxoglutarate transaminase"
                     /EC_number="2.6.1.19"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009448 - gamma-aminobutyric acid
                     metabolic process [Evidence IEA]"
                     /calculated_mol_wt=45571
     Region          1..425
                     /region_name="PRK08088"
                     /note="4-aminobutyrate--2-oxoglutarate transaminase"
                     /db_xref="CDD:236149"
     Site            order(110..112,138..139,141,206,239,241..242,268)
                     /site_type="active"
                     /note="inhibitor-cofactor binding pocket [active]"
                     /db_xref="CDD:99735"
     Site            order(111..112,138..139,206,239,242,268)
                     /site_type="other"
                     /note="pyridoxal 5'-phosphate binding site [chemical
                     binding]"
                     /db_xref="CDD:99735"
     Site            268
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:99735"
ORIGIN      
        1 mssnkelmqr rsqaiprgvg qihpifadra encrvwdveg reyldfaggi avlntghlhp
       61 kvvaaveaql kklshtcfqv layepylelc eimnqkvpgd fakktllvtt gseavenavk
      121 iaraatkrsg tiafsgayhg rthytlaltg kvnpysagmg lmpghvyral ypcplhgise
      181 ddaiasihri fkndaapedi aaiviepvqg eggfyaatpa fmqrlralcd ehgimliade
      241 vqsgagrtgt lfameqmgva pdlttfaksi aggfplagvt graevmdava pgglggtyag
      301 npiacvaale vlkvfeqenl lqkandlgqk lkdgllaiae khpeigdvrg lgamiaielf
      361 edgdhnkpda kltaeivara rdkglillsc gpyynvlril vpltiedaqi rqgleiisqc
      421 faeakq