MULTISPECIES: helix-turn-helix domain-containing protein

LOCUS       WP_000095669             320 aa            linear   BCT 21-JAN-2025
            [Escherichia].
ACCESSION   WP_000095669
VERSION     WP_000095669.1
KEYWORDS    RefSeq.
SOURCE      Escherichia
  ORGANISM  Escherichia
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae.
REFERENCE   1  (residues 1 to 320)
  AUTHORS   Aravind,L., Anantharaman,V., Balaji,S., Babu,M.M. and Iyer,L.M.
  TITLE     The many faces of the helix-turn-helix domain: transcription
            regulation and beyond
  JOURNAL   FEMS Microbiol Rev 29 (2), 231-262 (2005)
   PUBMED   15808743
REFERENCE   2  (residues 1 to 320)
  AUTHORS   Rosinski,J.A. and Atchley,W.R.
  TITLE     Molecular evolution of helix-turn-helix proteins
  JOURNAL   J Mol Evol 49 (3), 301-309 (1999)
   PUBMED   10473770
REFERENCE   3  (residues 1 to 320)
  AUTHORS   Wintjens,R. and Rooman,M.
  TITLE     Structural classification of HTH DNA-binding domains and
            protein-DNA interaction modes
  JOURNAL   J Mol Biol 262 (2), 294-313 (1996)
   PUBMED   8831795
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10617438
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Escherichia"
                     /db_xref="taxon:561"
     Protein         1..320
                     /product="helix-turn-helix domain-containing protein"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /calculated_mol_wt=35680
     Region          24..71
                     /region_name="HTH_36"
                     /note="Helix-turn-helix domain; pfam13730"
                     /db_xref="CDD:463970"
     Region          <28..>185
                     /region_name="PRK15313"
                     /note="intestinal colonization autotransporter adhesin
                     MisL"
                     /db_xref="CDD:237940"
     Region          <300..320
                     /region_name="DnaT"
                     /note="DnaT DNA-binding domain; cl46275"
                     /db_xref="CDD:480615"
ORIGIN      
        1 mssklhglvw egcaftgmil srvavmarla dysndegvsw paietirrqi garsestvks
       61 aiaelakegw ltkeerkvgg rnvsniyrln vekleaaaaa aresykpkrk ispakndplt
      121 vdpsniapst vdpsnfdgst vdnklpirga midpdpsvlk pdpsdkrssc pdasqpdpqt
      181 aeqnfltrhp davvfsakkr qwgsqedlvc aqwiwgrivs lyeqaasddg eitrpkepnw
      241 tawandvrtm rmldgrthrq icemfgrlqr dsfwvknims paklrekwde lvirlgrspa
      301 qrcvnhisep dteippgfrg