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N-ethylmaleimide reductase [Escherichia coli].


LOCUS       WP_000093602             365 aa            linear   BCT 10-JUL-2019
ACCESSION   WP_000093602
VERSION     WP_000093602.1
KEYWORDS    RefSeq.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Escherichia.
REFERENCE   1  (residues 1 to 365)
  AUTHORS   Gray,M.J., Wholey,W.Y., Parker,B.W., Kim,M. and Jakob,U.
  TITLE     NemR is a bleach-sensing transcription factor
  JOURNAL   J. Biol. Chem. 288 (19), 13789-13798 (2013)
   PUBMED   23536188
REFERENCE   2  (residues 1 to 365)
  AUTHORS   Lee,C., Shin,J. and Park,C.
  TITLE     Novel regulatory system nemRA-gloA for electrophile reduction in
            Escherichia coli K-12
  JOURNAL   Mol. Microbiol. 88 (2), 395-412 (2013)
   PUBMED   23506073
REFERENCE   3  (residues 1 to 365)
  AUTHORS   Robins,K.J., Hooks,D.O., Rehm,B.H. and Ackerley,D.F.
  TITLE     Escherichia coli NemA is an efficient chromate reductase that can
            be biologically immobilized to provide a cell free system for
            remediation of hexavalent chromium
  JOURNAL   PLoS ONE 8 (3), e59200 (2013)
   PUBMED   23527133
REFERENCE   4  (residues 1 to 365)
  AUTHORS   Gonzalez-Perez,M.M., van Dillewijn,P., Wittich,R.M. and Ramos,J.L.
  TITLE     Escherichia coli has multiple enzymes that attack TNT and release
            nitrogen for growth
  JOURNAL   Environ. Microbiol. 9 (6), 1535-1540 (2007)
   PUBMED   17504490
REFERENCE   5  (residues 1 to 365)
  AUTHORS   Williams,R.E., Rathbone,D.A., Scrutton,N.S. and Bruce,N.C.
  TITLE     Biotransformation of explosives by the old yellow enzyme family of
            flavoproteins
  JOURNAL   Appl. Environ. Microbiol. 70 (6), 3566-3574 (2004)
   PUBMED   15184158
REFERENCE   6  (residues 1 to 365)
  AUTHORS   Miura,K., Tomioka,Y., Suzuki,H., Yonezawa,M., Hishinuma,T. and
            Mizugaki,M.
  TITLE     Molecular cloning of the nemA gene encoding N-ethylmaleimide
            reductase from Escherichia coli
  JOURNAL   Biol. Pharm. Bull. 20 (1), 110-112 (1997)
   PUBMED   9013822
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR008072
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..365
                     /organism="Escherichia coli"
                     /db_xref="taxon:562"
     gene            1..365
                     /gene="nemA"
     Protein         1..365
                     /product="N-ethylmaleimide reductase"
                     /EC_number="1.3.1.-"
                     /calculated_mol_wt=39415
     Region          4..365
                     /region_name="PRK10605"
                     /note="N-ethylmaleimide reductase; Provisional"
                     /db_xref="CDD:182584"
     Site            order(25,27,59,101,234,302,322,324..326)
                     /site_type="other"
                     /note="FMN binding site [chemical binding]"
                     /db_xref="CDD:239243"
     Site            order(25,27,59,101,103,110,182,185,187,234,241,302,322,
                     324..325)
                     /site_type="active"
                     /db_xref="CDD:239243"
     Site            order(27,103,182,185,187,325)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:239243"
     Site            187
                     /site_type="active"
                     /note="catalytic residue [active]"
                     /db_xref="CDD:239243"
ORIGIN      
        1 msseklyspl kvgaitaanr ifmapltrlr siepgdiptp lmaeyyrqra sagliiseat
       61 qisaqakgya gapgihspeq iaawkkitag vhaenghmav qlwhtgrish aslqpggqap
      121 vapsalsagt rtslrdengq airvetsmpr aleleeipsi vndfrqaian areagfdlve
      181 lhsahgyllh qflspssnhr tdqyggsven rarlvlevvd agieewgadr igirvspigt
      241 fqntdngpne eadalylieq lgkrgiaylh msepdwagge pytdafrekv rarfhgpiig
      301 agaytvekae tligkglida vafgrdwian pdlvarlqrk aelnpqraes fygggaegyt
      361 dyptl